Esoz 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Esomeprazole
Company Astra biopharmaceuticals ltd
Also available as
Esoz 20 mg tablet Esoz 20 mg capsule

Indications

  • Chronic heartburn relief
  • GERD symptoms relief
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Helicobacter pylori eradication
  • Zollinger-Ellison Syndrome treatment
  • Acid-related Dyspepsia relief
  • Duodenal ulcer treatment
  • Gastric ulcer treatment

Pharmacology

  • Proton pump inhibitor
  • Specific inhibition of H+/K+-ATPase
  • First single optical isomer of proton pump inhibitor
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation
  • Peak plasma levels at approximately 1.5 hours
  • Extensive metabolism in the liver
  • Plasma elimination half-life of approximately 1-1.5 hours

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Dosage for healing of erosive esophagitis
  • Dosage for maintenance of healing of erosive esophagitis
  • Dosage for symptomatic GERD
  • Dosage for Helicobacter pylori eradication
  • Dosage for Zollinger-Ellison Syndrome
  • Dosage for acid-related Dyspepsia
  • Dosage for duodenal and gastric ulcer
  • Dosage for pediatric patients
  • Dosage for risk reduction of ulcer rebleeding following endoscopy

Administration

  • Swallowed whole
  • Taken one hour before a meal
  • Oral suspension instructions
  • IV injection instructions

Interaction

  • Extensive metabolism in the liver by CYP2C19 and CYP3A4
  • Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
  • Potential interference with CYP2C19
  • Inhibition of gastric acid secretion
  • Co-administration with other drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Frequently occurring adverse events
  • Including headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion in milk not studied
  • Breastfeeding discontinuation if essential use of esomeprazole

Precautions & Warnings

  • Symptomatic response does not preclude presence of gastric malignancy
  • Administration time and method
  • Information for patients
  • Use in special populations

Overdose Effects

  • Lethal dose in rats
  • Major signs of acute toxicity
  • No specific antidote
  • Symptomatic and supportive treatment

Storage Conditions

  • Temperature and moisture requirements
  • Protection from light
  • Keep out of reach of children

Chemical Structure

  • Molecular formula
  • Chemical structure image

Common Questions about Esoz 40 mg Capsule

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  • Uses of Esoz 40 mg Capsule
  • Side effects of Esoz 40 mg Capsule
  • Pregnancy and breastfeeding considerations
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  • Quick tips

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