Esoz 40 mg (Capsule (Enteric Coated))
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Astra biopharmaceuticals ltd |
| Also available as |
Indications
- Chronic heartburn relief
- GERD symptoms relief
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Helicobacter pylori eradication
- Zollinger-Ellison Syndrome treatment
- Acid-related Dyspepsia relief
- Duodenal ulcer treatment
- Gastric ulcer treatment
Pharmacology
- Proton pump inhibitor
- Specific inhibition of H+/K+-ATPase
- First single optical isomer of proton pump inhibitor
- Better acid control than racemic proton pump inhibitors
- Enteric-coated pellet formulation
- Peak plasma levels at approximately 1.5 hours
- Extensive metabolism in the liver
- Plasma elimination half-life of approximately 1-1.5 hours
Dosage
- Oral dosage form
- IV Injection or IV infusion
- Dosage for healing of erosive esophagitis
- Dosage for maintenance of healing of erosive esophagitis
- Dosage for symptomatic GERD
- Dosage for Helicobacter pylori eradication
- Dosage for Zollinger-Ellison Syndrome
- Dosage for acid-related Dyspepsia
- Dosage for duodenal and gastric ulcer
- Dosage for pediatric patients
- Dosage for risk reduction of ulcer rebleeding following endoscopy
Administration
- Swallowed whole
- Taken one hour before a meal
- Oral suspension instructions
- IV injection instructions
Interaction
- Extensive metabolism in the liver by CYP2C19 and CYP3A4
- Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
- Potential interference with CYP2C19
- Inhibition of gastric acid secretion
- Co-administration with other drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Frequently occurring adverse events
- Including headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects observed in animal studies
- Excretion in milk not studied
- Breastfeeding discontinuation if essential use of esomeprazole
Precautions & Warnings
- Symptomatic response does not preclude presence of gastric malignancy
- Administration time and method
- Information for patients
- Use in special populations
Overdose Effects
- Lethal dose in rats
- Major signs of acute toxicity
- No specific antidote
- Symptomatic and supportive treatment
Storage Conditions
- Temperature and moisture requirements
- Protection from light
- Keep out of reach of children
Chemical Structure
- Molecular formula
- Chemical structure image
Common Questions about Esoz 40 mg Capsule
- Overview of Esoz 40 mg Capsule
- Uses of Esoz 40 mg Capsule
- Side effects of Esoz 40 mg Capsule
- Pregnancy and breastfeeding considerations
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