Cazep 200 mg (Tablet)

Unit Price: ৳ 4.02 (5 x 10: ৳ 201.00)
Strip Price: ৳ 40.20

Medicine Details

Indications

  • partial and secondary generalized tonic-clonic seizures
  • Primary generalized tonic-clonic seizures
  • Trigeminal neuralgia
  • Prophylaxis of bipolar disorder

Pharmacology

Carbamazepine depresses activity in the nucleus ventralis of the thalamus, reduces synaptic propagation of excitatory impulses or decreases summation of temporal stimulation leading to neural discharge by limiting influx of Na ions across cell membrane or other unknown mechanisms.

Dosage & Administration

  • Initial dosage for adults and children over 12 years of age
  • Dosage for children 12-15 years of age
  • Dosage for children 6-12 years of age
  • Dosage for children under 6 years of age
  • Combination therapy
  • Dosage for Trigeminal Neuralgia
  • Maintenance dosage
  • Instructions for administration with meals

Interaction

Interaction with oral contraceptives and hepatic enzyme inducers

Contraindications

  • Problems with the electrical message pathways in the heart (atrioventricular block)
  • History of decreased blood cell production by the bone marrow (bone marrow depression)
  • Hereditary blood disorders called porphyrias
  • Allergy to tricyclic antidepressants
  • Usage within 14 days of monoamine-oxidase inhibitor antidepressant (MAOI)

Side Effects

  • Dizziness
  • Drowsiness
  • Ataxia
  • Dry mouth
  • Abdominal pain
  • Nausea
  • Vomiting
  • Leucopenia
  • Proteinuria
  • Bradycardia
  • Heart failure
  • Hypotension
  • Erythematous skin rash
  • Aplastic anemia
  • Increased sensitivity to the sun

Pregnancy & Lactation

Pregnancy category D. Transfer to breast milk. Potential serious side effects.

Precautions & Warnings

  • Caution with potentially hazardous activities
  • Skin reactions
  • Liver problems
  • Depletion of hormonal contraceptives
  • Need for gradual discontinuation
  • Specific caution for certain conditions

Therapeutic Class

Primary anti-epileptic drugs

Storage Conditions

Keep below 30°C, away from light & moisture, out of the reach of children

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