Decason 0.05% (Ophthalmic Ointment)

Indications

• Treatment of allergic non-infectious blepharitis and conjunctivitis
• Treatment of non-infectious keratitis, punctate keratitis, disciform keratitis
• Treatment of inflammation of the anterior uvea (iritis, iridocyclitis)
• Treatment of scleritis, episcleritis and myositis
• Post-operative management of cataract, strabismus & other ocular surgeries

Pharmacology

• Active ingredient: Dexamethasone, a cortisone derivative
• Anti-inflammatory, anti-allergic, anti-exudative and anti-proliferative properties
• Rapid penetration into cornea and aqueous humor after local application
• Inhibition of phospholipase A2 and prostaglandin synthesis
• Inhibition of neutrophil infiltration into the site of inflammation

Dosage & Administration

• Dexamethasone ophthalmic solution: Instill 1 drop into the conjunctival sac 3-5 times per day
• Acute cases: up to 1 drop every hour if necessary
• Dexamethasone ophthalmic ointment: Apply a small amount into the conjunctival sac 3-4 times per day
• Instructions for application and dosing adjustments

Interaction

• Specific drug interaction studies not conducted

Contraindications

• Injuries and ulcerating processes of the cornea
• Purulent infections of the conjunctiva and eyelids
• Tuberculosis, mycosis, glaucoma

Side Effects

• Reversible rise in intraocular pressure in predisposed patients

Pregnancy & Lactation

• Adverse effects on the fetus in animal experiments
• Use during pregnancy only if potential benefit justifies potential risk to the fetus

Precautions & Warnings

• Corticosteroids may mask, activate or aggravate an infection
• Instructions for use if no improvement is seen after a few days
• Avoid touching dropper tip to any surface

Overdose Effects

• Overdose via local or accidental oral administration unlikely

Storage Conditions

• Store at room temperature
• Protect from light
• Desirable to not use more than one month after opening

Related Brands

• Decason 0.1% (Ophthalmic Solution) - opsonin-pharma-ltd