Emer 200 mg/ml (Injection)
1 ml ampoule: ৳ 16.05 (1 x 5: ৳ 80.25)
Medicine Details
| Category | Details |
|---|---|
| Generic | Phenobarbital |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Sedatives
- Hypnotics for the short-term treatment of insomnia
- Pre-anesthetics
- Long-term anticonvulsants for the treatment of generalized tonic-clonic and cortical local seizures
- Emergency control of certain acute convulsive episodes
Description
- Barbiturate
- Nonselective
- Central nervous system depressant
- Primarily used as a sedative hypnotic
- Also used as an anticonvulsant in subhypnotic doses
Pharmacology
- Acts on GABA(A) receptors
- Increases synaptic inhibition
- Elevates seizure threshold
- Reduces the spread of seizure activity from a seizure focus
- May inhibit calcium channels
Dosage & Administration
- Pediatric oral dosage: Preoperative, Anticonvulsant
- Adult oral dosage: Daytime sedative, Bedtime hypnotic, Anticonvulsant
- Pediatric injection dosage: Preoperative sedation, Anticonvulsant
- Adult injection dosage: Insomnia, Convulsions, Status Epilepticus
Interaction
- Concomitant use of Alcohol or other CNS depressants may produce additive CNS depressant effects
Contraindications
- Known Phenobarbital sensitivity
- History of latent porphyria
Side Effects
- Somnolence
- Agitation
- Confusion
- Hyperkinesia
- Ataxia
- CNS depression
- Nightmares
- Nervousness
- Psychiatric disturbance
- Hallucinations
- Insomnia
- Anxiety
- Dizziness
- Thinking abnormality
- Apnea
- Bradycardia
- Hypotension
- Nausea
- Vomiting
- Constipation
Pregnancy & Lactation
- Pregnancy Category D
- Potential hazard to the fetus
- Caution in nursing women
Precautions & Warnings
- Tolerance and psychological and physical dependence may occur with continuing use
- Administer with caution to mentally depressed patients
- Administer with caution to patients with suicidal tendencies
- Administer with caution to patients with a history of drug abuse
- Administer with caution to patients with hepatic damage
- Initial reduced doses for patients with hepatic damage
Overdose Effects
- Toxic dose varies considerably
- CNS and respiratory depression
- Immediate hospitalization necessary
Therapeutic Class
- Adjunct anti-epileptic drugs
- Barbiturates
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children