Noxarin 8000 Anti-Xa IU/0.8 ml (SC Injection)

0.8 ml pre-filled syringe: ৳ 650.00

Medicine Details

Category Details
Generic Enoxaparin sodium
Company Opsonin pharma ltd
Also available as
Noxarin 2000 anti xa injection Noxarin 4000 anti xa injection Noxarin 6000 anti xa injection

Indications

  • Treatment of deep vein thrombosis, with or without pulmonary embolism
  • Treatment of unstable angina and non-Q-wave myocardial infarction
  • Prevention of thrombus formation in the extra-corporeal circulation during hemodialysis
  • Prophylaxis of venous thromboembolic disease in orthopedic or general surgery patients
  • Prophylaxis of venous thromboembolic disease in medical patients bedridden due to acute illness

Composition

  • Enoxaparin Sodium BP 20 mg equivalent to 2000 anti-Xa III
  • Enoxaparin Sodium BP 40 mg equivalent to 4000 anti-Xa III
  • Enoxaparin Sodium BP 60 mg equivalent to 6000 anti-Xa IU
  • Enoxaparin Sodium BP 80 mg equivalent to 8000 anti-Xa IU

Pharmacology

Low molecular weight heparin with high anti-Xa activity and low anti-lla activity. Metabolised in the liver.

Dosage

  • Subcutaneously administered for various conditions
  • Oral anticoagulant therapy initiation
  • Recommended doses for different surgical procedures
  • Different doses for patients with a high risk of hemorrhage

Administration

  • Instructions on self-injection
  • Preparing the injection site
  • Selecting the correct dose
  • Injecting the medication
  • Disposal of used syringes

Interaction

Recommendations for discontinuation of agents affecting hemostasis prior to Noxarin therapy

Contraindications

  • Known hypersensitivity to Enoxaparin Sodium, heparin or other low molecular weight heparins
  • Active major bleeding
  • High risk of uncontrolled hemorrhage, including recent hemorrhagic stroke

Side Effects

  • Haemorrhage
  • Thrombocytopenia
  • Elevations of serum aminotransferase
  • Pain, bluish marks, or skin rash at injection sites
  • Potential for neuraxial hematomas with specific anesthesia

Pregnancy & Lactation

Pregnancy category B. No evidence of crossing the placental barrier. Use during pregnancy only if clearly needed. Caution in nursing mothers.

Precautions & Warnings

  • Injection routes: deep subcutaneous, intravascular
  • Not to be administered intramuscularly
  • Used with caution in conditions with increased potential for bleeding
  • Regular platelet count monitoring

Use in Special Populations

  • No dosage adjustment in elderly patients
  • Observation for signs and symptoms of bleeding in patients with renal impairment
  • Caution in hepatically impaired patients

Overdose Effects

Accidental overdosage may lead to hemorrhagic complications. Protamine sulfate can be used for neutralization.

Therapeutic Class

Parenteral anti-coagulants

Storage Conditions

Cool and dry place, protect from light and moisture, below 25°C, keep out of reach of children

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