Symbion (400 mcg+12 mcg)/puff (Inhaler)

60 metered doses: ৳ 1,100.00

Medicine Details

Category Details
Generic Budesonide formoterol fumarate
Company Beximco pharmaceuticals ltd
Also available as
Symbion 100 mcg inhalation capsule Symbion 200 mcg inhalation capsule Symbion 80 mcg inhaler Symbion 160 mcg inhaler Symbion 400 mcg inhalation capsule Symbion 100 mcg inhaler Symbion 200 mcg inhaler

Title

  • Dry Powder Inhaler with Formoterol Fumarate Dihydrate and Budesonide BP

Categories

  • Medicine
  • Respiratory Health
  • Inhalation Therapy

Description

  • Combination of Formoterol Fumarate Dihydrate BP and Budesonide BP
  • Anti-inflammatory action in the airways
  • Short onset of action
  • Long-acting relaxation of bronchial smooth muscle
  • Low incidence of adverse effects
  • Selective β2 adrenoceptor agonist
  • Oral inhalation only

Indications

  • Treatment of Asthma in patients 12 years and older
  • Maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD) in adults

Pharmacology

  • Budesonide: Potent glucocorticoid activity
  • Formoterol Fumarate Dihydrate: Long-acting β2 - adrenergic agonist with rapid onset of action
  • Anti-inflammatory effect of glucocorticosteroids
  • Stimulation of intracellular adenyl cyclase

Dosage

  • Recommended maintenance doses for different age groups
  • Twice-daily maintenance treatment
  • Reliever therapy
  • Alternative dosage regimens for asthma and COPD

Administration

  • Correct and regular usage to prevent or lessen severity of asthma attacks
  • Cleaning instructions for the inhaler
  • Proper technique for effective inhalation
  • Mirror check for correct inhalation

Interaction

  • Co-administration precautions with specific inhibitors and antidepressants
  • Caution with beta-blockers and diuretics for potential interactions

Contraindications

  • Primary treatment of status asthmaticus or acute episodes of asthma/COPD
  • Hypersensitivity to any ingredients

Side Effects

  • Potential adverse reactions of Formoterol Fumarate and Budesonide
  • Common, uncommon and rare adverse events associated with each compound

Pregnancy & Lactation

  • Limited clinical data on exposed pregnancies
  • Potential risk of the combination treatment for breastfeeding women
  • Adverse effects of Formoterol in pregnant women
  • Excretion of Budesonide in breast milk

Precautions & Warnings

  • Caution in patients with specific conditions such as diabetes mellitus, severe hypertension, and glaucoma
  • Potential for paradoxical bronchospasm

Use in Special Populations

  • Regular monitoring of children's height during prolonged treatment
  • Consideration of referring patients to a paediatric respiratory specialist

Overdose Effects

  • Typical effects of overdose with Formoterol
  • Potential symptoms from isolated cases
  • Chronic excessive doses of Budesonide

Storage Conditions

  • Inhalation capsule usage instructions
  • Storage temperature and protection from light and moisture
  • Safety precautions for handling and storing

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