Deflaxen 6 mg (Tablet)
Unit Price: ৳ 9.50 (3 x 10: ৳ 285.00)
Strip Price: ৳ 95.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Everest pharmaceuticals ltd |
| Also available as |
Title
- Deflaxen Tablet
Categories
- Medicine
- Pharmaceutical
Description
- Deflaxen tablet is prescribed for the treatment of various conditions such as anaphylaxis, asthma, rheumatoid arthritis, lupus, dermatomyositis, nephrotic syndrome, leukemia, and more.
DosageRangeAdults
3-120 mg/day
DosageRangeChildren
0.25-1.5 mg/kg/day
DosageDetails
- Doses should be titrated to the lowest effective dose for maintenance.
- Alternate day administration may be suitable for children.
Pharmacology
Deflazacort provides anti-inflammatory action by inhibiting Phospholipase A2 enzyme and decreases the release of certain chemicals important in the immune system.
MetabolismLocation
Liver
DrugInteraction
- LiverEnzymeInducers:
- rifampicin
- carbamazepine
- phenytoin
- phenobarbitone
- LiverEnzymeInhibitors:
- ketoconazole
Contraindications
- Hypersensitivity to any of the ingredients
- Patients receiving live virus immunization
SideEffects
- GI disturbances
- musculoskeletal issues
- endocrine disturbances
- neuropsychiatric effects
- ophthalmic issues
- fluid and electrolyte disturbances
- increased susceptibility to infections
- impaired healing
- hypersensitivity reactions
- skin atrophy
- striae
- telangiectasia
- acne
- thromboembolism
PregnancyAndLactation
- PregnancyRisk: May increase the risk of intrauterine growth retardation if used for prolonged periods or repeatedly during pregnancy.
- LactationRisk: Doses of up to 50 mg daily are unlikely to cause systemic effects in the infant.
PrecautionsAndWarnings
- Caution is necessary in cardiac disease, hypertension, thromboembolic disorders
- Special caution needed in patients with osteoporosis, myasthenia gravis, emotional instability, psychotic tendency, epilepsy, liver failure
- Caution in patients with ocular herpes simplex due to possible corneal perforation
SpecialPopulationsUse
- HepaticImpairment: Carefully monitor and adjust the dose
- RenalImpairment: No special precautions necessary
- Elderly: Adverse effects may be associated with more serious consequences in old age
TherapeuticClass
Glucocorticoids
StorageConditions
Store below 25°C, protected from light & moisture, keep out of the reach of children