Amoxikil 500 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Veritas pharmaceuticals ltd |
Indications
- Ear, nose and throat infections
- Lower respiratory tract infections
- Skin and soft tissue infections
- Genito-urinary tract infections
- Venereal disease
- Treatment of H. pylori infection
- Dental abscess
Pharmacology
Amoxicillin is a broad spectrum penicillin effective against a wide range of bacteria. It inhibits cell wall biosynthesis and is stable in gastric acid.
Dosage
- Adult: 250 mg three times daily
- Children: 125 mg three times daily
- Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
- Otitis media (adult): 1 g three times daily
- Otitis media (children): 40 mg/kg body weight daily in 3 divided doses (max. 3 g daily)
- Pneumonia: 500-1000 mg three times daily
- Dental abscess: 3 gm, repeated after 10-12 hours
- Urinary tract infections: 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm
Administration
Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, or water.
Interaction
Concurrent use of Amoxikil and Probenecid may result in increased and prolonged blood levels of Amoxikil. Amoxikil may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side Effects
- Diarrhoea
- Indigestion
- Rash
- Pseudo-membranous colitis (rarely reported)
Pregnancy & Lactation
- Pregnancy Category: B
- Caution for lactating mothers: Amoxicillin has been shown to be excreted in human milk. Caution should be exercised when Amoxicillin is administered to a lactating mother.
Precautions & Warnings
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Amoxikil should be discontinued and appropriate therapy should be instituted.
Therapeutic Class
Broad spectrum penicillins
Reconstitution
- Amoxycillin 500 mg Injection (Intramuscular): Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial.
- Amoxycillin 500 mg Injection (Intravenous): Dissolve Amoxycillin 500 mg injection in 10 ml water for injection.
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.