Ceftrimax 1 gm/vial (IM Injection)

1 gm vial: ৳ 190.57

Medicine Details

Title and Categories

  • Ceftrimax (Ceftriaxone)

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Potent bactericidal activity
  • Interferes with bacterial cell wall synthesis
  • High stability in the presence of beta lactamases
  • Long plasma elimination half-life
  • Not metabolized in the body
  • Highly protein bound

Dosage

  • 1 to 2 gm dose for adults by intravenous or intramuscular administration once a day
  • 250 mg IM dose for uncomplicated gonococcal infections
  • 1 g IV dose for surgical prophylaxis
  • 50 to 75 mg/kg dose for infants and children (01 month or older)
  • Duration of therapy: 4 to 14 days; longer therapy for complicated infections

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Dissolving in Lidocaine HCI 1% or Water for injection
  • Administered over 2-4 minutes
  • Freshly reconstituted solution recommended
  • Patient tolerance test before treatment

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis following IV administration

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution in lactating mothers due to excretion in human milk

Precautions & Warnings

  • Possibility of anaphylactic shock
  • Shadows suggesting sludge in gallbladder
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

  • Avoid use in premature and newborn neonates (up to 28 days of age)

Overdose Effects

  • No specific antidote; Treatment should be symptomatic

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Keep away from light and moisture
  • Keep out of the reach of children

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