Esover 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 9.03 (3 x 10: ৳ 270.90)
Strip Price: ৳ 90.30

Medicine Details

Category Details
Generic Esomeprazole
Company Veritas pharmaceuticals ltd
Also available as
Esover 20 mg capsule

Product Title

  • Esover 40 mg Capsule

Product Categories

  • Medicine
  • Gastrointestinal Health
  • Pharmaceuticals

Indications

  • Relief from chronic heartburn symptoms
  • Treatment of symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Treatment of duodenal & gastric ulcers

Mode of Action

  • Proton pump inhibitor
  • Specific inhibition of the H+/K+-ATPase in gastric parietal cells
  • First single optical isomer of proton pump inhibitor
  • Better acid control than racemic proton pump inhibitors
  • Peak plasma levels occur at approximately 1.5 hours after oral administration
  • Extensively metabolized in the liver
  • Plasma elimination half-life of approximately 1–1.5 hours

Dosage Form

  • Oral tablets
  • Oral suspension
  • IV injection
  • IV infusion

Dosage Instructions

  • Dosage varies for different indications
  • Oral dose to be taken one hour before a meal
  • IV injection duration: >3 minutes, IV infusion duration: 10-30 minutes

Administration

  • Tablet or capsule should be swallowed whole
  • Oral suspension should be taken with water and consumed within 30 minutes
  • IV injection solution to be administered intravenously over a period of at least 3 minutes

Interactions

  • Extensively metabolized by CYP2C19 and CYP3A4
  • No clinically significant interactions with certain drugs
  • Has potential to interfere with the absorption of drugs where gastric pH is important for bioavailability

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No excretion of esomeprazole in milk studies
  • Breastfeeding should be discontinued if esomeprazole use is essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Dosage adjustments for hepatic insufficiency
  • No dosage adjustment recommended for renal insufficiency

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy observed between the elderly and younger individuals

Overdose Effects

  • Toxic dose lethal to rats
  • Major signs include reduced motor activity, changes in respiratory frequency, tremor, ataxia, and intermittent clonic convulsions

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions

  • What is esomeprazole used for?
  • What are the side effects of esomeprazole?
  • Can esomeprazole be taken during pregnancy or breastfeeding?
  • How long does it take for esomeprazole to work?
  • Quick tips for using esomeprazole

Related Brands