Pregaver 75 mg (Capsule)

Unit Price: ৳ 19.00 (2 x 10: ৳ 380.00)
Strip Price: ৳ 190.00

Medicine Details

Category Details
Generic Pregabalin
Company Veritas pharmaceuticals ltd
Also available as
Pregaver 25 mg capsule Pregaver 50 mg capsule

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)

Dosage

  • DPN in adults: 50-300 mg/day
  • PHN in adults: 75-600 mg/day
  • Fibromyalgia in adults: 300-450 mg/day
  • Neuropathic pain associated with spinal cord injury in adults: 150-600 mg/day

Administration

  • Route of administration: Oral
  • Dosage form: CR tablet
  • Administration instructions: Swallow whole, do not split, crush, or chew
  • Discontinuation: Gradual tapering over a minimum of 1 week

Interaction

  • Drug interaction with medication: Unlikely significant pharmacokinetic interactions
  • Drug interaction with food and others: Not applicable

Contraindications

Known hypersensitivity to Pregabalin or its components

Side Effects

  • Most common in adults:
    • Dizziness
    • Somnolence
    • Dry mouth
    • Edema
    • Blurred vision
    • Weight gain
    • Thinking abnormal
  • Most common in pediatric patients:
    • Increased weight
    • Increased appetite

Pregnancy & Lactation

No adequate and well-controlled studies, detected in the milk of lactating women, not recommended during breastfeeding

Precautions & Warnings

  • Angioedema can occur and may be associated with life threatening respiratory compromise
  • Discontinue immediately in case of hypersensitivity reactions
  • Increase in suicidal thoughts or behavior
  • Respiratory depression may occur
  • May cause dizziness and somnolence, impairing ability to drive or operate machinery
  • Caution when coadministering with thiazolidinedione antidiabetic agents

Use in Special Populations

Safety and effectiveness in pediatric patients have not been established

Overdose Effects

Reduced consciousness, depression/anxiety, seizures, heart block, no specific antidote

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

Cool & dry place (below 30°C), protected from light & moisture

Chemical Structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg

Commonly Asked Questions

  • What is Pregaver 75 mg Capsule?: An anticonvulsant and first-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
  • How long do I need to use Pregaver 75 mg Capsule before I see improvement in my condition?: Until improvement is seen
  • At what frequency do I need to use Pregaver 75 mg Capsule?: As prescribed by the doctor
  • Should I use Pregaver 75 mg Capsule empty stomach, before food or after food?: After food in prescribed dosage
  • What are the instructions for the storage and disposal of Pregaver 75 mg Capsule?: Keep in a cool dry place, in its original packaging, out of reach of children and pets

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