Verifen SR 100 mg (Capsule (Sustained Release))

Unit Price: ৳ 3.01 (10 x 10: ৳ 301.00)
Strip Price: ৳ 30.10

Medicine Details

Indications

  • Rheumatology
  • Surgery and Traumatology
  • Obstetrics and Gynecology
  • Otorhinolaryngology
  • Dentistry
  • Other indications

Pharmacology

Potent non-steroidal anti-inflammatory drug (NSAID) with pronounced anti-rheumatic, anti-inflammatory, analgesic and antipyretic properties

Dosage & Administration

  • Diclofenac FC Tablet: Adults: 75-150 mg daily in 2 to 3 divided doses, preferably after food. Dose should be reduced in long term use.
  • Diclofenac SR Tablet:
    • Adults: 1 tablet daily, taken whole with liquid, preferably at meal times. If necessary, the daily dose can be increased to 150 mg by supplementation with conventional tablets.
    • Children: 1-3 mg of diclofenac/kg body wt. daily in divided doses.
    • Elderly patients: In elderly or debilitated patients, the lowest effective dosage is recommended, although the pharmacokinetics of diclofenac sodium is not impaired to any clinically relevant extent in elderly patients.
  • Diclofenac Dispersible Tablet:
    • Adults: The recommended daily dosage is 2-3 tablets and the maximum daily dose is 150 mg. In milder cases, 2 tablets of Diclofenac DT per day are sufficient. Diclofenac DT should preferably be taken before meals.
    • Children: Diclofenac is not recommended in children for other indications except juvenile rheumatoid arthritis where the recommended dose is 1-3 mg/kg body weight.
  • Diclofenac TR Capsule: One capsule daily. Diclofenac TR should be taken preferably after mealtimes.
  • Diclofenac Suppository: For adults: 50 mg suppository 2-3 times daily. Maximum daily dose is 150 mg.
  • Diclofenac injection: For adults the usual dose is 1 ampoule daily. In serious cases this dose may be increased up to 2 ampoules daily.
  • Diclofenac Gel: For external use only. Depending on the size of area to be treated, 2-4 g of Diclofenac gel should be applied to the skin 3-4 times daily.

Interaction

  • Lithium and digoxin
  • Anticoagulants
  • Antidiabetic agents
  • Cyclosporin
  • Methotrexate
  • Quinolone antimicrobials
  • Other NSAIDs and steroids

Contraindications

Hypersensitive patients, peptic ulcer patients, asthmatic patient precipitated by acetylsalicylic acid, Gel use under occlusive airtight dressings

Side Effects

  • Epigastric pain
  • Eructation
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Peripheral edema
  • Skin reactions
  • Rash
  • Eczema
  • Local skin irritation
  • Reddening of the skin
  • Skin rash

Pregnancy & Lactation

Should be employed only for compelling reasons, lowest effective dose should be used, not recommended during the first trimester of pregnancy, Gel not recommended during pregnancy, insignificant quantity in breast milk

Precautions & Warnings

Close observation for peptic ulceration or gastrointestinal bleeding, close observation for advanced age patients, avoiding contact with eyes or mucus membranes, proper hand washing after application, not to be taken by mouth

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Store in a cool and dry place, protected from light, store below 30°C, keep out of the reach of children

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