Adrebloc 100 mg/10 ml (IV Injection)
10 ml vial: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esmolol hydrochloride |
| Company | Zas corporation |
Title
- Adrebloc
Categories
- Medicine
- Pharmaceuticals
Description
- Beta adrenergic blocker with rapid onset and short duration of action.
Dimensions
- Not applicable
Color Options
- Not applicable
Functions
- Control of ventricular rate in supraventricular tachycardia
- Control of heart rate in noncompensatory sinus tachycardia
- Control of perioperative tachycardia and hypertension
Materials
- Esmolol Hydrochloride
Technical Specifications
- Beta-1 selective (cardioselective) adrenergic receptor blocking agent
- Elimination half-life after intravenous infusion is approximately 9 minutes
Design Elements
- Not applicable
Usability Features
- Administered intravenously
- Rapid onset of action
- Short duration of action
Indications
- Short-term treatment of ventricular rate control in supraventricular tachycardia
- Control of perioperative tachycardia and hypertension
Pharmacology
- Selective inhibition of beta 1 receptors in cardiac muscle
- No significant intrinsic sympathomimetic or membrane stabilizing activity at therapeutic dosages
Dosage & Administration
- Intravenous administration
- Titration using ventricular rate or blood pressure
- Loading dose for gradual control of tachycardia and hypertension
Interaction
- Potential interactions with digitalis glycosides, anticholinesterases, antihypertensive agents, sympathomimetic drugs, vasoconstrictive, and positive inotropic effect substances
Contraindications
- Severe sinus bradycardia
- Higher degree heart block
- Sick sinus syndrome
- Decompensated heart failure
- Cardiogenic shock
- Coadministration of IV cardiodepressant calcium-channel antagonists
- Pulmonary hypertension
- Known hypersensitivity to esmolol
Side Effects
- Symptomatic hypotension
- Asymptomatic hypotension
Pregnancy & Lactation
- Pregnancy Category C
- Increased fetal resorptions in animal studies
- No adequate and well-controlled studies in pregnant women
- Unknown excretion in human milk
Precautions & Warnings
- Risk of hypotension, bradycardia, and cardiac failure
- Exacerbating reactive airway disease
- Effect on diabetes mellitus
- Unopposed alpha-agonism and severe hypertension in untreated pheochromocytoma
- Risk of myocardial ischemia upon abrupt discontinuation in patients with coronary artery disease
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- Geriatric use not extensively studied
- No special precautions in hepatic impairment
- No dosage adjustment in renal impairment
Therapeutic Class
- Anti adrenergic agent (Beta blockers)
Storage Conditions
- Keep below 25°C
- Protect from light and moisture
- Keep out of the reach of children