Dexporil (20 mg+10 mg+2.5 mg)/5 ml (Syrup)

Indications

• Relieves symptoms of common cold
• Relieves symptoms of hay fever
• Relieves symptoms of allergic rhinitis
• Relieves cough due to throat irritation
• Relieves cough due to bronchial irritation
• Relieves runny nose
• Relieves sneezing
• Relieves itching of the nose or throat
• Relieves itchy, watery eyes
• Relieves nasal congestion
• Reduces swelling of nasal passages

Pharmacology

• Contains antitussive
• Contains decongestant
• Contains antihistamine
• Dextromethorphan acts on cough center in medulla
• Phenylephrine shrinks blood vessels in nasal passage
• Triprolidine provides relief from conditions triggered by histamine release
• Triprolidine has mild CNS depressant properties

Dosage

• Adult dosage: 1 teaspoonful every 4 hours
• Children (6-12 years) dosage: ½ teaspoonful every 4 hours
• Caution advised for children (2-6 years)
• Not to be used in children below 2 years old

Administration

• Can be taken with or without food
• Recommended to measure liquid doses carefully
• Use the provided measuring device for accurate dosing

Interaction

• May interact with MAO inhibitors
• Should be used with caution with certain antihistamines
• Should be used with caution with certain beta blockers
• Should be used with caution with certain inhaled anesthetics
• Should be used with caution with certain narcotic pain relievers

Contraindications

• Avoid in patients with liver disease
• Avoid in asthmatic patients
• Contraindicated in patients taking monoamine oxidase inhibitors
• Contraindicated within 2 weeks from stopping MAO inhibitors
• Contraindicated in patients with severe hypertension
• Contraindicated in patients with severe coronary artery disease

Side Effects

• May cause drowsiness
• May cause constipation
• Other side effects may include GIT discomfort, transient hypertension, dry mouth, restlessness, palpitations
• Less common side effects may include allergic reactions, tight chest, thickening of bronchial secretions, toxic psychosis, blood dyscrasia

Pregnancy & Lactation

• Use in pregnancy and lactation is best avoided

Precautions & Warnings

• May cause drowsiness
• Avoid driving or operating machinery if affected
• Avoid alcoholic drinks while on this medication
• Use with caution in patients with epilepsy, prostatic hypertrophy, glaucoma, hepatic disease, hypertension, heart disease, diabetes
• Use with caution in patients with hyperthyroidism, stenosing peptic ulcer, pyloro-duodenal obstruction, bladder neck obstruction
• Consult a physician if symptoms do not improve within one week or are accompanied by high fever

Overdose Effects

• Hospital admission advised in cases of overdose
• May produce respiratory depression, paranoid psychosis, delusions, hallucinations, convulsions
• Treatment includes emptying the stomach, sedative administration, and supportive measures

Therapeutic Class

• Combined cough suppressants

Storage Conditions

• Keep out of reach of children
• Keep in a cool, dry place
• Protect from light

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