Migesic 200 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Tolfenamic acid
Company Renata limited

Category

  • Pain Relief
  • Analgesic
  • NSAID

DosageForm

Tablet

AvailableStrengths

  • 200 mg

Indications

  • Relieving migraine headache pain
  • Post-operative pain relief
  • Fever reduction

Pharmacology

Inhibits cyclooxygenase enzyme, inhibits prostaglandin synthesis, has direct antagonistic action on prostaglandin receptors

Pharmacokinetics

  • Absorption: Readily absorbed from GI tract
  • PeakPlasmaConcentration: 60-90 min
  • Bioavailability: 85%
  • ProteinBinding: 99%
  • PlasmaHalfLife: 2 hours
  • Metabolism: Metabolised in the liver
  • Excretion: Excreted in urine (90%) and feces

Interaction

  • Increased absorption with Metoclopramide
  • Decreased absorption with Aluminium hydroxide
  • Risk of bleeding with anticoagulants and other NSAIDs
  • Decreased antihypertensive response with loop diuretics, B-blockers, and ACE Inhibitors

Contraindications

  • Active gastrointestinal bleeding
  • Gastrointestinal ulceration
  • Severe heart failure

SideEffects

  • Alveolitis
  • Hepatic damage
  • Pancreatitis
  • Pulmonary eosinophilia
  • Stevens-johnson syndrome
  • Angioedema
  • Blood disorder
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dysuria
  • Euphoria
  • Gastrointestinal bleeding
  • Nausea
  • Hearing disturbances
  • Rash
  • Visual disturbances
  • Vertigo
  • Hypertension
  • Overdose symptoms: headache, vomiting, gastrointestinal bleeding, drowsiness, dizziness, convulsion

PregnancyAndLactation

Not recommended during pregnancy, caution during breastfeeding due to low concentrations in breast milk

PrecautionsAndWarnings

  • Patients with asthma bronchospasm
  • Bleeding disorders
  • Cardiovascular diseases
  • Peptic ulceration
  • Hypertension
  • Liver infection
  • Elderly patients
  • Increased water intake or dose reduction to reduce dysuria

OverdoseEffects

  • Headache
  • Nausea
  • Vomiting
  • Gastrointestinal bleeding
  • Diarrhea
  • Excitation
  • Coma
  • Symptomatic treatment required

TherapeuticClass

  • Rheumatoid Arthritis
  • NSAIDs
  • Migraine treatment

StorageConditions

Store in cool, dry place away from light and out of reach of children

ChemicalStructure

  • MolecularFormula: C14H12ClNO2
  • StructureImageURL: https://medex.com.bd/storage/res/g-res-1092-tolfenamic-acid-chemical-structure-dzPweN5r9IE4mD1xFrIL.svg

CommonQuestions

  • What is Migesic 200 mg Tablet?
  • What are the uses of Migesic 200 mg Tablet?
  • Quick tips for using Migesic 200 mg Tablet

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