Prazia 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Esomeprazole
Company Amico laboratories ltd
Also available as
Prazia 20 mg capsule

Title:

  • Prazia 40 mg Capsule

Categories

  • Medicine
  • Health & Wellness
  • Gastrointestinal Health

Description

  • Prazia is a proton pump inhibitor indicated for various conditions including heartburn, GERD, erosive esophagitis, H. pylori infection, Zollinger-Ellison Syndrome, and more.

Brand

  • Prazia

Dosage form

  • Oral tablet
  • Oral suspension
  • IV injection
  • IV infusion

Indication

  • Relief from chronic heartburn
  • Treatment of GERD symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Helicobacter pylori eradication
  • Zollinger-Ellison Syndrome treatment
  • Treatment of acid-related dyspepsia
  • Duodenal and gastric ulcer treatment

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • First single optical isomer of proton pump inhibitor
  • Better acid control than racemic proton pump inhibitors
  • Absorption, Distribution, Metabolism, Excretion (ADME) profile

Mode of action

  • Suppression of gastric acid secretion by inhibition of H+/K+-ATPase

Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • Potential interference with CYP2C19
  • Possible interference with absorption of certain drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy lactation

  • No adequate and well-controlled studies in pregnant women
  • No excretion data in milk
  • Breast-feeding discontinuation recommendation

Precautions warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Instructions for patient regarding capsule swallowing and administration with applesauce

Special populations

  • No established safety and efficacy in paediatric patients
  • No observed differences in safety and efficacy between elderly and younger individuals
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in renal impairment

Overdose effects

  • Acute toxicity signs in animal studies
  • Symptomatic and supportive treatment in case of overdose

Storage conditions

  • Temperature not exceeding 30°C
  • Dry place
  • Protection from light and moisture
  • Keep out of reach of children

Chemical structure

  • Molecular formula: C17H19N3O3S

Commonly asked questions

  • What is Prazia 40 mg Capsule?
  • Uses of Prazia 40 mg Capsule
  • Side effects of Prazia 40 mg Capsule
  • Safety during pregnancy or breastfeeding
  • Onset of action
  • Quick Tips for usage

Compound summary

  • Molecular formula: C17H19N3O3S
  • Chemical structure image available

Administration

  • Tablet or capsule: Swallowed whole and taken one hour before a meal
  • Oral suspension: Mixed with water and consumed within 30 minutes
  • Iv injection: Preparation with 0.9% Sodium Chloride, administered intravenously over at least 3 minutes

Dosage

  • Oral:
    • Dosage for different indications
    • Oral administration instructions
  • IV Injection or IV infusion:
    • Dosage for GERD with Erosive Esophagitis in adult and pediatric patients
    • Risk reduction of rebleeding of Gastric or Duodenal Ulcers following therapeutic endoscopy in adults

Pediatric use

No established safety and effectiveness

Geriatric use

No overall differences in safety and efficacy observed

Hepatic insufficiency

No dosage adjustment recommended for mild to moderate hepatic insufficiency

Renal insufficiency

Pharmacokinetics not expected to be altered relative to healthy volunteers

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