Zodef 6 mg (Tablet)
Unit Price: ৳ 9.50 (3 x 10: ৳ 285.00)
Strip Price: ৳ 95.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Renata limited |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Lupus erythematosus
- Dermatomyositis
- Polyartritis nodosa
- Minimal change nephrotic syndrome
- Rheumatic carditis
- Ulcerative colitis
- Uveitis
- Haemolytic anaemia
- Thrombocytopenic purpura
- Leukaemia
- Lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
Provides anti-inflammatory action by inhibiting Phospholipase A2 enzyme; decreases release of certain immune system chemicals
Dosage & Administration
- Adult dosage: up to 120 mg/day for acute disorders
- Maintenance doses for most conditions: 3-18 mg/day
- Children dosage: 0.25-1.5 mg/kg/day for juvenile chronic arthritis, nephrotic syndrome, and bronchial asthma
- Deflazacort withdrawal advice
Interaction
Metabolized in the liver; recommended adjustments with liver enzyme inducers and inhibitors
Contraindications
Hypersensitivity to ingredients; patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Increased susceptibility to infection
- Impaired healing
Pregnancy & Lactation
Crosses placenta; increased risk of intrauterine growth retardation with prolonged use during pregnancy; excreted in breast milk
Precautions & Warnings
- Special caution for cardiac disease
- Gastritis or oesophagitis
- Diabetes mellitus
- Emotional instability or psychotic tendency
- Liver failure
- Ocular herpes simplex
Use in Special Populations
- Hepatic impairment: monitor and adjust dose
- Renal impairment: normal precautions
- Elderly: normal precautions
Therapeutic Class
Glucocorticoids
Storage Conditions
Store below 25°C, protected from light & moisture