Zodef 24 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Renata limited |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Severe hypersensitivity reactions
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute and lymphatic leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibition of Phospholipase A2 enzyme
- Prostaglandin synthesis inhibition
- Immunosuppressive action
Dosage & Administration
- Adults:
- For acute disorders: Up to 120 mg/day initially
- Maintenance doses range: 3-18 mg/day
- Rheumatoid arthritis maintenance dose: 3-18 mg/day
- Bronchial asthma treatment doses: 48-72 mg/day
- Children: 0.25-1.5 mg/kg/day
Interaction
- Metabolized in the liver
- Maintenance dose adjustment with co-administered liver enzyme inducers
- Maintenance dose adjustment with liver enzyme inhibitors
Contraindications
- Hypersensitivity to ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine system effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Increased susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Myocardial rupture
- Thromboembolism
Pregnancy & Lactation
- Risk of intrauterine growth retardation
- Corticosteroid excretion in breast milk
- Adrenal suppression in infants of mothers taking higher doses
Precautions & Warnings
- Cardiac disease monitoring
- Hypertension monitoring
- Thromboembolic disorders monitoring
- Gastritis or oesophagitis caution
- Diverticulitis caution
- Ulcerative colitis caution
- Diabetes mellitus monitoring
- Osteoporosis monitoring
- Myasthenia gravis monitoring
- Renal insufficiency caution
- Emotional instability monitoring
- Psychotic tendency caution
- Epilepsy monitoring
- Corticosteroid-induced myopathy history
- Liver failure caution
- Hypothyroidism caution
- Cirrhosis caution
- Ocular herpes simplex caution
Use in Special Populations
- Hepatic impairment monitoring
- Renal impairment caution
- Elderly monitoring
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Cool and dry place
- Protected from light & moisture