Dezacot 24 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute leukaemia
- Lymphatic leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibition of Phospholipase A2 enzyme
- Prostaglandin synthesis inhibition
- Immunosuppressive action
- Decrease in release of certain immune system chemicals
Dosage & Administration
- Adults dosing range: 3-120 mg/day
- Children dosing range: 0.25-1.5 mg/kg/day
- Maintenance doses within specified ranges for various conditions
- Alternate day administration in children
- Guidance for dose reduction during withdrawal
Interaction
- Metabolism in the liver
- Increased maintenance dose with liver enzyme inducers
- Possible dose reduction with liver enzyme inhibitors
Contraindications
- Hypersensitivity to any of the ingredients
- Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Myocardial rupture risk
- Thromboembolism risk
Pregnancy & Lactation
- Crossing the placenta
- Potential risk of intrauterine growth retardation
- Excretion in breast milk
- Infant adrenal suppression risk
- Benefits of breastfeeding vs theoretical risk consideration
Precautions & Warnings
- Special caution for certain clinical conditions
- Frequent patient monitoring
- Management of salt and water retention
- Potassium supplementation if necessary
- Caution with certain gastrointestinal conditions
- Caution with diabetes mellitus or family history
- Osteoporosis caution
- Caution in emotional instability or psychotic tendency
- Caution in patients with epilepsy
- Caution in liver failure
- Hypothyroidism and cirrhosis caution
- Ocular herpes simplex caution
Use in Special Populations
- Hepatic impairment monitoring and dose adjustment
- No special precautions in renally impaired patients
- No special precautions in elderly patients
Therapeutic Class
- Glucocorticoids
Storage Conditions
- Cool and dry storage below 25°C
- Protection from light and moisture
- Keep out of the reach of children