Thelin 15 mg (Tablet)
Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Propantheline bromide |
| Company | Incepta pharmaceuticals ltd |
Indications
- Adjunctive therapy in the treatment of peptic ulcer (gastric and duodenal)
- Relief of the symptoms of gastritis (stomach upset, gastrointestinal bleeding, blood in vomit, blood in stool, persistent pain)
- Symptomatic treatment of the diarrhea related irritable bowel syndrome (irritable colon, spastic colon, acute enterocolitis, functional Gl disorders etc)
- Urinary incontinence
- Control of salivation and enuresis
- Improves lactose intolerance
- Prevents excessive sweating (Hyperhidrosis)
Pharmacology
- Dual mechanism of action
- Anticholinergic effect (antimuscarinic)
- Direct effect upon smooth muscle (musculotropic)
Dosage & Administration
- Usual initial adult dose of 75 mg daily
- One tablet 30 min before each meal (15 mg three times daily)
- Two tablets at bedtime
- Maximum daily dosage of 120 mg
- Pediatric use not established
Interaction
- Reduced absorption with antacids or absorbent antidiarrheals
- Delayed absorption with anticholinergics
- Significant drug interaction with digoxin, haloperidol, corticosteroids, ketoconazole, levodopa, opioid analgesics, phenothiazines, urinary alkalizers
Contraindications
- Hypersensitivity to Propantheline bromide or other anticholinergic agents
- Glaucoma
- Obstructive disease of the gastrointestinal tract (pyloroduodenal stenosis, paralytic ileus etc.)
- Obstructive uropathy (e.g. prostatic hypertrophy) intestinal atony of elderly
- Myasthenia gravis
Side Effects
- Dose-related adverse effects
- Reversible upon discontinuation
- Dry mouth
- Dry skin
- Mydriasis
- Urinary retention
- Nausea
- Vomiting
- Constipation
- Headache
- Nervousness
- Mental confusion
Pregnancy & Lactation
- Pregnancy category C
- Caution in pregnant and nursing women
- Possible excretion in milk
- Suppression of lactation
Precautions & Warnings
- Caution in the elderly
- Caution in patients with autonomic neuropathy, hepatic or renal disease, hyperthyroidism, coronary heart disease, congestive heart failure, cardiac tachyarrhythmias, hypertension
Overdose Effects
- Intensification of side effects
- CNS disturbances
- Circulatory changes
- Respiratory failure
- Paralysis
Therapeutic Class
- Anticholinergics (antimuscarinics)/ Anti-spasmodics
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children