Doxotor 2 mg/ml (IV Infusion)
10 mg vial: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxorubicin hydrochloride |
| Company | Eskayef pharmaceuticals ltd |
Indications
- Adjuvant chemotherapy for breast cancer
- Treatment of leukemia
- Treatment of lymphoma
- Treatment of metastatic cancer
Pharmacology
Cytotoxic, anthracycline topoisomerase II inhibitor
Dosage & Administration
- Dosage range
- Administration route
- Incompatibility with other drugs
- Management of suspected extravasation
- Intravenous infusion guidelines
Interaction
- Substrate of cytochrome P450 CYP3A4 and CYP2D6
- P-glycoprotein (P-gp) interactions
- Drug-drug interaction precautions
Contraindications
- Severe myocardial insufficiency
- Recent myocardial infarction
- Hepatic impairment
- Hypersensitivity
Side Effects
- Alopecia
- Nausea and vomiting
- Cardiomyopathy and arrhythmias
- Secondary malignancies
- Extravasation and tissue necrosis
- Myelosuppression
- Tumor lysis syndrome
- Radiation sensitization
Pregnancy & Lactation
- Pregnancy Category D
- Fetal harm potential
- Contraception advice
- Excretion in human milk
- Nursing consideration
Use in Special Populations
- Pediatric use
- Cardiovascular monitoring for pediatric patients
- Geriatric use
- Hepatic impaired patients
Overdose Effects
- Symptoms of overdose
- Fatal doses
- Delayed cardiac failure
- Monitoring and support
Therapeutic Class
Cytotoxic Chemotherapy
Reconstitution
- Preparation for Administration
- Precautions during Handling
- Storage condition after reconstitution
Storage Conditions
Dry place, 2-8°C, Protect from light, Do not freeze