Gemtor 200 mg/vial (IV Infusion)
200 mg vial: ৳ 1,400.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Gemcitabine |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Non-Small Cell Lung Cancer
- Pancreatic Cancer
- Bladder Cancer
- Breast Cancer
- Ovarian Cancer
Pharmacology
- DNA synthesis inhibition
- Nucleoside kinases metabolism
- Cytotoxic action
- Inhibition of ribonucleotide reductase
- DNA polymerase inhibition
- Apoptosis induction
Dosage & Administration
- Dosing regimens for different types of cancer
- Intravenous infusion
- Week on, week off cycle
- Dosage reduction based on toxicity
- Combination use with other drugs
Interaction
- No confirmed interactions reported
- No specific drug interaction studies
Contraindications
- Known hypersensitivity to Gemcitabine
Side Effects
- Haematological Toxicity
- Hepatic Toxicity
- Gastrointestinal effects
- Genito-Urinary Toxicity
- Pulmonary Toxicity
- Allergic Toxicity
- Neurotoxicity
- Alopecia
Pregnancy & Lactation
- Pregnancy Category D
- Unknown excretion in breast milk
Precautions & Warnings
- Caution in patients with specific risks
- Respiratory Failure
- Hemolytic Uremic Syndrome
- Embryofetal Toxicity
- Impairment of Fertility
Use in Special Populations
- Elderly Patients tolerance
- Renal and Hepatic Impairment caution
- Limited usage in children
Overdose Effects
- No known antidote
- Myelosuppression
- Paresthesias
- Severe rash
- Monitoring and supportive therapy
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Temperature and light-sensitive storage instructions
- Avoid refrigeration
- Keep out of reach of children