Erdon-Plus (75 mg+20 mg)/2 ml (IM Injection)

2 ml ampoule: ৳ 15.00 (2 x 5: ৳ 150.00)

Medicine Details

Title

  • Diclofenac Sodium and Lidocaine Injection

Categories

  • Pain Relief
  • Anti-inflammatory
  • Analgesic
  • Local Anesthetic
  • Arthritis Medication
  • Musculoskeletal Disorder Treatment
  • Postoperative Pain Relief
  • Renal Colic Treatment
  • Osteoarthritis Medication
  • Rheumatoid Arthritis Medication

Description

  • The injection contains Diclofenac Sodium and Lidocaine used for relief of pain and inflammation in various conditions including arthritic and musculoskeletal disorders, trauma-related pain, control of pain and inflammation in surgeries, renal colic, and other painful conditions.
  • Diclofenac Sodium is a potent nonsteroidal antiinflammatory drug (NSAID) with marked analgesic and antipyretic properties.
  • Lidocaine acts as a local anaesthetic, minimizing pain at the injection site when used in the indications mentioned.

Packaging dimensions

  • 5ml ampoule

Color options

  • Clear liquid

Dosage form

  • Injection

Age recommendations

  • Adult
  • Children
  • Elderly patients

Administration route

  • Intramuscular

Pharmacology

  • Diclofenac Sodium inhibits prostaglandin synthesis by inhibiting cyclooxygenase, while Lidocaine impairs nerve impulse generation and conduction by slowing depolarization.

Onset of action

  • 30 minutes following injection

Interactions

  • Lithium and Digoxin
  • Anticoagulants
  • Antidiabetic agents
  • Cyclosporin
  • Methotrexate
  • Quinolone antimicrobials
  • Other NSAIDs and steroids
  • Diuretics

Contraindications

  • Hypersensitivity to Diclofenac or local anaesthetics of the amide type
  • Patients with active or suspected peptic ulcer or gastrointestinal bleeding
  • Patients in whom attacks of asthma, urticaria or acute rhinitis are precipitated by Aspirin or other NSAIDs possessing prostaglandin synthetase inhibiting activity.
  • Patients with Adams-Stokes syndrome or severe degrees of heart block
  • Hypersensitivity to any of the excipients used in the formulation

Side effects

  • Gastrointestinal discomfort
  • Nausea
  • Diarrhea
  • Bleeding
  • Injection site disorder
  • Abscesses
  • Local necrosis
  • CNS reactions like drowsiness, dizziness, disorientation, confusion, lightheadedness

Pregnancy precautions

  • Not recommended during the last trimester of pregnancy
  • Should not be prescribed during pregnancy unless compelling reasons exist
  • Lowest effective dosage should be used
  • Minimal quantities detected in breast milk

Special precautions warnings

  • Close observation in patients with severe hepatic, cardiac or renal insufficiency, or the elderly
  • Deterioration of renal function may result from NSAID use
  • Monitor renal, hepatic function, and blood counts in long-term NSAID treatment
  • Discontinue Diclofenac if abnormal liver function tests persist or worsen, clinical signs or symptoms of liver disease develop, or other manifestations occur

Therapeutic class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage conditions

  • Store at temperature not exceeding 30°C in a dry place. Protected from light.

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