Danflex 50 mg (Capsule)

Unit Price: ৳ 15.00 (2 x 10: ৳ 300.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Dantrolene sodium
Company Opsonin pharma ltd
Also available as
Danflex 25 mg capsule

Title

Danflex

Categories

  • Medicine
  • Pharmacology
  • Muscle Relaxant
  • Healthcare

Description

Danflex is a centrally acting skeletal muscle relaxant used in the treatment of chronic spasticity resulting from conditions such as spinal cord injury, stroke, cerebral palsy, or multiple sclerosis. It is also indicated to prevent or attenuate the development of signs of malignant hyperthermia in known or strongly suspect malignant hyperthermia susceptible patients who require anesthesia and/or surgery.

Attributes

  • Indications:
    • Control of clinical spasticity
    • Beneficial in functional rehabilitation
    • Prevention of malignant hyperthermia
  • Pharmacology:
    • Affects skeletal muscle contractile response
    • Interferes with release of Ca++ from sarcoplasmic reticulum
  • Dosage & Administration:
    • Gradual titration schedule for adults
    • Gradual titration schedule for paediatric patients
    • Preoperative and post-crisis dosing for malignant hyperthermia
  • Interaction:
    • Potential drowsiness with CNS depressants
    • Increased risk of hepatotoxicity with concomitant estrogen therapy
  • Contraindications:
    • Active hepatic disease
  • Side Effects:
    • Drowsiness
    • Dizziness
    • Weakness
    • Diarrhea
    • General malaise
    • Fatigue
  • Pregnancy & Lactation:
    • Pregnancy Category C
    • Use in nursing mothers not recommended
  • Precautions & Warnings:
    • Liver function monitoring
    • Caution in driving and hazardous occupations
    • Possible photosensitivity reaction
    • Potential for liver damage with long-term use
    • Caution in concomitant administration of tranquilizing agents
    • Caution in patients with impaired pulmonary function
  • Use in Special Populations:
    • Long-term safety in paediatric patients under 5 years not established
  • Therapeutic Class:
    • Centrally acting Skeletal Muscle Relaxants
  • Storage Conditions:
    • Store in a cool & dry place, protected from light

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