Vorinox 200 mg (Tablet)

Unit Price: ৳ 110.00 (1 x 10: ৳ 1,100.00)
Strip Price: ৳ 1,100.00

Medicine Details

Indications

  • Invasive aspergillosis
  • Candidemia
  • Disseminated candidiasis
  • Esophageal candidiasis
  • Scedosporium apiospermum infections
  • Fusarium Species infections

Pharmacology

  • Triazole antifungal medication
  • Inhibition of CYP450-dependent 14-alpha sterol demethylase
  • Depletion of ergosterol in fungal cell membrane

Dosage & Administration

  • Oral administration
  • Loading dose regimen
  • Maintenance dose regimen
  • Injection administration
  • Different dosages for different infections
  • Instructions based on body weight
  • As directed by physician

Interaction

  • CYP3A4 inhibitors and inducers
  • CYP2C9 inhibitors and inducers
  • CYP2C19 inhibitors and inducers
  • Effect on other drug concentrations and activity
  • Adjustment of Vorinox dosage
  • Monitoring for adverse reactions

Contraindications

  • Hypersensitivity to Voriconazole
  • Co-administration with specific drugs
  • Risk of serious adverse reactions
  • Risk of loss of efficacy

Side Effects

  • Abdominal pain
  • Anemia
  • Blurred vision
  • Headache
  • Chest pain
  • Nausea
  • Diarrhea

Pregnancy & Lactation

  • Limited studies in pregnant women
  • Use only if potential benefit justifies potential risk to fetus

Precautions & Warnings

  • Assessment of benefit-risk balance for long-term exposure
  • Reports of squamous cell carcinoma of the skin with long-term treatment

Use in Special Populations

  • Efficacy not established in children under 12 years of age

Overdose Effects

  • No data available about overdose effects

Therapeutic Class

  • Other Antifungal preparations

Reconstitution

  • Instructions for suspension reconstitution
  • Shaking the bottle before adding water
  • Adding specific amount of water
  • Storage and discard instructions

Storage Conditions

  • Keep out of reach of children
  • Store in dry place below 25°C
  • Store powder for suspension between 2°C to 8°C

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