Sperid 2 mg (Tablet)

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Indications

  • Acute and chronic psychoses
  • Mania
  • Schizophrenia

Pharmacology

Selective monoaminergic antagonist with high affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors

Dosage & Administration

  • Psychoses:
    • 2 mg in 1-2 divided doses on 1st day then 4 mg in 1-2 divided doses on second day
    • Usual dose range 4-6 mg daily
    • Elderly or in hepatic or renal impairment initially 1 mg daily in two divided doses increased in steps of 1-2 mg twice daily
  • Mania:
    • Initially, 2 mg once daily increased if necessary in step of 1 mg daily
    • Usual dose range 1-6 mg daily
    • Elderly or in hepatic or renal impairment initially 1 mg daily in two divided doses increased in steps of 1-2 mg twice daily
  • Schizophrenia:
    • Administered at 1 mg BID initially, with increases in increments of 1 mg BID on the second and third day, as tolerated, to a target dose of 3 mg BID by the third day
    • Further dosage adjustments should generally occur at intervals of not less than 1 week

Interaction

May antagonize the effects of levodopa and dopamine agonists. Chronic administration with Carbamazepine reduces plasma clearance of the drug. Chronic administration with Clozapine may decrease the clearance of the drug. May enhance the effects of certain antihypertensives

Contraindications

Known hypersensitivity to the product

Side Effects

  • Insomnia
  • Agitation
  • Anxiety
  • Headache
  • Drowsiness
  • Impaired concentration
  • Fatigue
  • Blurred vision
  • Constipation
  • Nausea and vomiting
  • Dyspepsia
  • Abdominal pain
  • Hyperprolactinaemia
  • Tachycardia
  • Hypertension
  • Edema
  • Rash
  • Rhinitis
  • Cerebrovascular accident
  • Neutropenia
  • Thrombocytopenia

Pregnancy & Lactation

Not established for use during human pregnancy. Excreted in the milk. Women receiving the drug should not breastfeed

Precautions & Warnings

  • Preexisting cardiovascular diseases
  • Discontinue use if signs and symptoms of tardive dyskinesia occur
  • Renal and hepatic impairment
  • Elderly
  • Epilepsy
  • Parkinson's disease
  • Pregnancy

Therapeutic Class

Atypical neuroleptic drugs

Storage Conditions

Do not store above 30°C. Keep away from light and out of the reach of children

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