Thyrox 100 mcg (Tablet)
Unit Price: ৳ 3.10 (1 x 60: ৳ 186.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Levothyroxine sodium |
| Company | Renata limited |
| Also available as |
Indications
- Replacement therapy in hypothyroidism
- Suppressing TSH levels
- Suppressing goitrogenic effects
- Diagnostic aid in suppression tests
Pharmacology
- Contains synthetic Levothyroxine
- Identical to natural hormone T4
- Conversion to T3 in peripheral tissues
- Major carrier of T4 is TBG
- Long half-life in circulation
- Liver is major site of degradation
- Enterohepatic circulation of Thyroid hormones
Dosage & Administration
- Initial starting dose: 25-50 mcg/day
- Gradual increments in dose at 6-8 week intervals
- Adjustment based on clinical and laboratory assessment
- Pediatric dosage based on age and weight
Interaction
- Concurrent use of tri/tetracyclic antidepressants
- Administration of sertraline
- Addition to antidiabetic or insulin therapy
- Careful monitoring of diabetic control
Contraindications
- Untreated subclinical or overt Thyrotoxicosis
- Acute Myocardial Infarction
- Uncorrected Adrenal failure
Side Effects
- Fatigue
- Weight loss
- Heat intolerance
- Headache
- Tremors
- Palpitations
- Diarrhea
- Hair loss
Pregnancy & Lactation
- Pregnancy Category A
- Caution in administration to nursing women
Precautions & Warnings
- Treatment of adrenocortical insufficiency
- Careful dosing in patients with cardiovascular disease
- Adjustment of dosage based on body weight change
- Monitoring blood levels of T3 and T4
Overdose Effects
- Signs and symptoms of hyperthyroidism
- Agitation
- Confusion
- Irritability
- Tachycardia
- Increased bowel movements
Therapeutic Class
Thyroid drugs & hormone
Storage Conditions
Store below 30°C, dry place, protect from light