Epicet 500 mg (Tablet)

Unit Price: ৳ 30.00 (1 x 10: ৳ 300.00)
Strip Price: ৳ 300.00

Medicine Details

Indications

  • Monotherapy in treatment of partial-onset seizures
  • Adjunctive therapy for various types of seizures

Description

  • Mechanism of action is unknown
  • Minimal activity in submaximal stimulation
  • Inhibition of burst firing without affecting normal neuronal excitability

Dosage

  • Adult starting dose 250 mg twice daily
  • Maximum dose 1500 mg twice daily
  • Children under 6 should use oral solution

Administration

  • Tablets must be taken orally with liquid
  • Administered in two divided doses

Interactions

  • Little influence on antiepileptic medicinal products
  • Inhibition of renal clearance of primary metabolite by probenecid
  • Concomitant use with methotrexate may increase its concentration to toxic levels

Contraindications

  • Hypersensitivity to active substance or pyrrolidone derivatives

Side Effects

  • Common adverse reactions include somnolence, asthenia, infection, dizziness

Pregnancy & Lactation

  • Not recommended during pregnancy and breastfeeding

Precautions & Warnings

  • Dose adjustment in renal impairment
  • Rare cases of decreased blood cell counts reported
  • Risk of suicidal thoughts and behaviors
  • Tablet formulation not for infants and children under age 6

Use in Special Populations

  • Dose adjustment in elderly and renal impairment
  • No dose adjustment needed in mild to moderate hepatic impairment

Overdose Effects

  • Symptoms include somnolence, agitation, respiratory depression
  • No specific antidote available

Therapeutic Class

  • Adjunct anti-epileptic drugs

Storage Conditions

  • Store at cool temperature not exceeding 25°C, dry place, protected from light

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