Epicet 250 mg (Tablet)

Unit Price: ৳ 16.00 (2 x 10: ৳ 320.00)
Strip Price: ৳ 160.00

Medicine Details

Category Details
Generic Levetiracetam
Company Renata limited
Also available as
Epicet 500 mg oral solution Epicet 500 mg tablet Epicet xr 500 mg tablet Epicet xr 750 mg tablet Epicet xr 1000 mg tablet Epicet 500 mg injection Epicet xr 1500 mg tablet

Indications

  • Monotherapy for partial-onset seizures in adults and adolescents
  • Adjunctive therapy for various types of seizures in adults, adolescents, children, and infants

Description

  • Mechanism of antiepileptic effect is unknown
  • Minimal activity in submaximal stimulation and threshold tests
  • Protection against secondarily generalized activity from induced seizures
  • Inhibition of burst firing without affecting normal neuronal excitability

Dosage

  • Recommended starting dose for adults and adolescents from 16 years of age
  • Initial therapeutic dose for adults (≥18 years) and adolescents (12 to 17 years) weighing 50 kg or more
  • Use of oral solution for pediatric population
  • No established safety and efficacy for monotherapy in children and adolescents below 16 years

Administration

  • Oral administration in two equally divided doses

Interaction

  • No influence on serum concentrations of existing antiepileptic medicinal products
  • Inhibition of renal clearance of methotrexate when administered concomitantly
  • Reports of decreased efficacy when administered with osmotic laxative macrogol

Contraindications

  • Hypersensitivity to the active substance or other pyrrolidone derivatives or to any of the excipients

Side Effects

  • Common adverse reactions in adult and pediatric patients
  • Incidence of somnolence, asthenia, infection, dizziness in adult patients
  • Incidence of fatigue, aggression, nasal congestion, decreased appetite, irritability in pediatric patients

Pregnancy & Lactation

  • Not recommended during pregnancy and lactation
  • Excretion in human breast milk

Precautions & Warnings

  • Dose adjustment for renal impairment
  • Rare cases of decreased blood cell counts
  • Risk of suicidal thoughts and behavior
  • Tablet formulation not adapted for use in infants and children under 6 years

Use in Special Populations

  • Recommended dose adjustment in elderly patients with compromised renal function
  • Individualized daily dose according to renal function in patients with renal impairment
  • No dose adjustment needed in patients with mild to moderate hepatic impairment

Overdose Effects

  • Adverse effects observed with overdose
  • Symptomatic treatment may include haemodialysis
  • No specific antidote available

Therapeutic Class

  • Adjunct anti-epileptic drugs

Storage Conditions

  • Store at a cool temperature (not exceeding 25°C) and dry place, protected from light

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