Odatron 4 mg/5 ml (Oral Solution)

50 ml bottle: ৳ 46.00

Medicine Details

Indications

  • Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy
  • Prevention and treatment of post-operative nausea and vomiting
  • Prevention of radiotherapy-induced nausea and vomiting

Dosage

  • 8 mg tablet/orodispersible tablet
  • 4 mg orodispersible tablet
  • Injection
  • Oral Solution
  • Highly emetogenic cancer chemotherapy
  • Moderate emetogenic cancer chemotherapy
  • Pediatric dose
  • Total body irradiation
  • Single high-dose fraction radiotherapy to the abdomen
  • Daily fractionated radiotherapy to the abdomen
  • Postoperative nausea and vomiting
  • Dosage Adjustment for Patients With Impaired Renal Function
  • Dosage Adjustment for Patients With Impaired Hepatic Function
  • 4 years of age or younger
  • Over the age of 65

Administration

  • Orally dissolving film designed to be applied on top of the tongue
  • Does not require water to aid dissolution or swallowing
  • Swallowed with saliva
  • Simple 5-step administration process

Interaction

Metabolized by hepatic cytochrome P-450 drug-metabolizing enzymes, inducers or inhibitors may change the clearance and half-life of Odatron

Contraindications

Contraindicated in patients known to have hypersensitivity to the drug or any of its components, Concomitant use of apomorphine

Side Effects

  • Headache
  • Constipation
  • Diarrhea
  • Rash
  • Sensation of flushing or warmth
  • Hiccups
  • Liver enzyme abnormalities
  • Anaphylaxis
  • Brochospasm
  • Tachycardia
  • Angina
  • Hypokalemia
  • Shortness of breath
  • No evidence of extrapyramidal reactions

Pregnancy & Lactation

No evidence of impaired fertility or harm to the fetus due to Ondansetron, Caution advised when administered to nursing women

Precautions & Warnings

  • Hypersensitivity reactions reported
  • Not a drug that stimulates gastric or intestinal peristalsis

Use in Special Populations

  • Dosage Adjustment for Patients With Impaired Renal Function
  • Dosage Adjustment for Patients With Impaired Hepatic Function
  • Little information for pediatric patients 4 years of age or younger
  • No dosage adjustment needed in patients over the age of 65

Therapeutic Class

Anti-emetic drugs

Storage Conditions

Store at temperature not exceeding 30°C in a dry place, Protect from light and moisture

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