Xelpro MUPS 20 mg (MUPS Tablet)

Unit Price: ৳ 11.00 (5 x 10: ৳ 550.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Esomeprazole mups preparation
Company Pharmasia limited

Title

  • Xelpro MUPS 20 Tablet
  • Xelpro MUPS 40 Tablet

Categories

  • Gastro-esophageal Reflux Disease (GERD)
  • NSAID associated gastric ulcer
  • H. pylori eradication
  • Zollinger-Ellison syndrome
  • Idiopathic hypersecretion

Indications

  • Risk reduction in NSAID associated gastric ulcer
  • H. pylori eradication (Triple therapy)
  • Zollinger-Ellison syndrome and idiopathic hypersecretion

Composition

  • 133.333 mg (15%w/w) of Esomeprazole enteric coated pellets equivalent to 20 mg Esomeprazole
  • 266.67 mg (15% w/w) of Esomeprazole enteric coated pellets equivalent to 40 mg Esomeprazole

Formulation

  • Multiple-Unit Pellet System (MUPS)
  • Modified release coated multiparticulates

Bioavailability

Ensures greater bioavailability

Drug Release

  • Rapid dissolution of enteric coating
  • Uniform drug release

Dosing

  • Once daily dosing
  • 40 mg once daily for 4 weeks
  • 20 mg once daily for maintenance of healing of erosive esophagitis

Administration

  • Swallow whole with liquid
  • Dispersible in non-carbonated water
  • Not to be chewed or crushed

Metabolism

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4

Drug Interactions

  • No clinically significant interactions with specific drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • Caution advised
  • Not known if Esomeprazole or its metabolites appear in human breast milk

Precautions

  • Severe liver dysfunction
  • Severe renal impairment
  • Increased risk of fracture with long-term use

Storage Conditions

Store in a cool & dry place below 25°C, protect from light, keep out of reach of children

Molecular Formula

C17H19N3O3S

Chemical Structure

Esomeprazole (MUPS preparation)

Common Questions

  • PPIs work by reducing the amount of acid produced in the stomach
  • Used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions
  • Aids in healing erosive esophagitis
  • Prevents erosive esophagitis recurrence
  • Common side effects may include headaches, diarrhea, and nausea

Quick Tips

  • Avoid eating late at night or before bedtime
  • Take adequate dietary intake of calcium and magnesium
  • Consult your doctor for any signs of kidney problems

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