Vomiren 0.5 mg (Capsule)

Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Palonosetron
Company Renata limited
Also available as
Vomiren 025 mg injection Vomiren 0075 mg injection Vomiren 05 mg tablet

Indications

  • Acute and delayed nausea and vomiting
  • Uncontrolled nausea and vomiting
  • Chemotherapy-induced nausea and vomiting (CINV)
  • Radiotherapy-induced nausea and vomiting (RINV)
  • Post-operative & Post-discharge nausea and vomiting (PONV & PDNV)

Pharmacology

  • 5-HT3 receptor antagonist
  • Strong binding affinity for 5-HT3 receptor
  • Little or no affinity for other receptors
  • Influence on postoperative nausea and vomiting
  • Inhibition of Serotonin actions
  • Metabolism and excretion pathways
  • Longer half-life

Dosage & Administration

  • Adult tablet dosage: 0.5 mg daily
  • Adult IV dosage: A single IV dose of 0.075 mg
  • Specific dosages for different types of nausea and vomiting
  • Children dosage based on body weight
  • Maximum dose for children
  • Dosage for different stages of chemotherapy and radiotherapy

Interaction

  • Safety with corticosteroids, analgesics, antiemetics/antinauseants, antispasmodics, and anticholinergic agents
  • No inhibitory effects on specific enzymes
  • Low potential for clinically significant drug interactions

Contraindications

  • Hypersensitivity to the drug or any of its components

Side Effects

  • Common adverse reactions: headaches and constipation

Pregnancy & Lactation

  • Pregnancy category 'B'
  • Unknown excretion in breast milk

Use in Special Populations

  • No dosage adjustment in elderly patients >65 years of age
  • Specific dosage for children
  • No dosage adjustment recommended in patients with renal and hepatic dysfunction

Overdose Effects

  • No known antidote
  • Management with supportive care

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Cool & dry place
  • Protected from light

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