Sergel MUPS 40 mg (MUPS Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole mups preparation |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Title
Sergel MUPS 40 mg Tablet
Categories
- Medicine
- Health
- Pharmaceutical
Description
Sergel MUPS tablet is a proton pump inhibitor used to treat gastro-esophageal reflux disease (GERD), risk reduction in NSAID associated gastric ulcer, H. pylori eradication, and Zollinger-Ellison syndrome.
Indications
- Gastro-esophageal Reflux Disease (GERD)
- Risk reduction in NSAID associated gastric ulcer
- H. pylori eradication (Triple therapy)
- Zollinger-Ellison syndrome and idiopathic hypersecretion
Composition
- Esomeprazole MUPS 20 Tablet
- Esomeprazole MUPS 40 Tablet
CompositionDetails
- Each MUPS tablet contains 133.333 mg (15%w/w) of Esomeprazole enteric coated pellets equivalent to 20 mg Esomeprazole (as Esomeprazole Magnesium Trihydrate USP)
- Each MUPS tablet contains 266.67 mg (15% w/w) of Esomeprazole enteric coated pellets equivalent to 40 mg Esomeprazole (as Esomeprazole Magnesium Trihydrate USP)
ModeOfAction
Inhibits gastric acid by blocking the hydrogen-potassium adenosine triphosphatase enzyme system (the proton pump) of the gastric parietal cell.
Dosage
- Erosive esophagitis - Adult (≥18 years): 40 mg once daily for 4 weeks
- Maintenance of healing of erosive esophagitis - Adult (≥18 years): 20 mg once daily
- Risk reduction in NSAID associated gastric ulcer - Adult (≥18 years): 20 mg once daily for 4-8 weeks
- H. pylori eradication - Adult (≥18 years): 20 mg twice daily for 7 days
- Zollinger-Ellison syndrome and idiopathic hypersecretion - Adult (≥18 years): 40-80 mg twice daily
Administration
Tablets should be swallowed whole with liquid or dispersed in non-carbonated water if necessary.
Interaction
Metabolized in the liver by CYP2C19 and CYP3A4, may interfere with the absorption of certain drugs.
Contraindications
Contraindicated in patients with known hypersensitivity to any of the formulation.
SideEffects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
PregnancyAndLactation
Caution advised, not known if Esomeprazole or its metabolites appear in human breast milk.
PrecautionsAndWarnings
- Severe liver dysfunction
- Severe renal impairment
- Increased risk of hip, wrist and spine fracture over long-term use
StorageConditions
Store in a cool & dry place below 25°C, protect from light, keep out of reach of children.
ChemicalStructure
- MolecularFormula: C17H19N3O3S
- ChemicalStructureImage: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg
CommonQuestions
- What is Sergel MUPS 40 mg MUPS Table?
- What is MUPS Tablet?
- What is Sergel MUPS 40 mg MUPS Table used for?
- What are the side effects of Sergel MUPS 40 mg MUPS Table?
- Can I take Sergel MUPS 40 mg MUPS Table if I am pregnant or breastfeeding?
- How long does it take for Sergel MUPS 40 mg MUPS Table to work?