DicloGel 1% w/w (Gel)
50 gm tube: ৳ 97.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatology
- Inflammatory forms of rheumatism
- Degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Pre-operative medication
- Post-operative pain
- Post-traumatic pain
- Pain and treatment of inflammation and swelling
- Renal and biliary colic
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic
- Analgesic
- Antipyretic
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Rapid and complete absorption from the gastrointestinal tract
- Metabolized in the liver
- First pass metabolism
- Peak plasma concentrations within 2 hours
Dosage & Administration
- Diclofenac FC Tablet for adults: 75-150 mg daily in 2 to 3 divided doses
- Diclofenac SR Tablet for adults: 1 tablet daily
- Diclofenac Dispersible Tablet for adults: 2-3 tablets daily
- Diclofenac TR Capsule: One capsule daily
- Diclofenac Suppository for adults: 50 mg 2-3 times daily
- Diclofenac injection for adults: 1 ampoule daily
- Diclofenac Gel for external use: 2-4 g applied 3-4 times daily
Interaction
- Increased plasma concentrations of lithium and digoxin
- Increased risk of hemorrhage with anticoagulant therapy
- No influence on antidiabetic agents' clinical effect
- Nephrotoxicity with cyclosporin concomitant use
- Serious toxicity with concomitant use of methotrexate and NSAIDs
- Convulsions with quinolones and NSAIDs concomitant therapy
- Increased frequency of unwanted effects with other NSAIDs and steroids
- Lowered plasma levels when co-administered with aspirin
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to Diclofenac
- Contra-indicated in asthmatic patients affected by certain drugs
- Not to be used under occlusive airtight dressings
Side Effects
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions
- Local irritation
- Reddening of the skin
- Skin rash
Pregnancy & Lactation
- Employed only for compelling reasons during pregnancy
- Lowest effective dose to be used during pregnancy
- Not recommended during the first trimester of pregnancy
- Very insignificant quantity detected in breast milk
Precautions & Warnings
- Close observation in patients with peptic ulceration or gastrointestinal bleeding
- Not to come in contact with eyes or mucus membranes
- Proper hand washing after application
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children