DicloGel 1% w/w (Gel)

50 gm tube: ৳ 97.00

Medicine Details

Category	Details
Generic	Diclofenac sodium
Company	Incepta pharmaceuticals ltd
Also available as	Intafenac 50 mg tablet

Indications

Rheumatology
Inflammatory forms of rheumatism
Degenerative forms of rheumatism
Chronic involutive
Polyarthritis
Ankylosing spondylarthritis
Osteoarthritis
Spondylarthroses
Acute gout
Peri-articular rheumatic disorders
Sprain
Bruises
Dislocations
Fractures
Soft tissue injuries
Surgical interventions
Primary dysmenorrhoea
Episiotomy
Adnexitis
Endometritis
Parametritis
Salpingitis
Mastitis
Pre-operative medication
Post-operative pain
Post-traumatic pain
Pain and treatment of inflammation and swelling
Renal and biliary colic

Pharmacology

Non-steroidal anti-inflammatory drug (NSAID)
Anti-rheumatic
Analgesic
Antipyretic
Uricosuric effect
Inhibition of prostaglandin biosynthesis
Rapid and complete absorption from the gastrointestinal tract
Metabolized in the liver
First pass metabolism
Peak plasma concentrations within 2 hours

Dosage & Administration

Diclofenac FC Tablet for adults: 75-150 mg daily in 2 to 3 divided doses
Diclofenac SR Tablet for adults: 1 tablet daily
Diclofenac Dispersible Tablet for adults: 2-3 tablets daily
Diclofenac TR Capsule: One capsule daily
Diclofenac Suppository for adults: 50 mg 2-3 times daily
Diclofenac injection for adults: 1 ampoule daily
Diclofenac Gel for external use: 2-4 g applied 3-4 times daily

Interaction

Increased plasma concentrations of lithium and digoxin
Increased risk of hemorrhage with anticoagulant therapy
No influence on antidiabetic agents' clinical effect
Nephrotoxicity with cyclosporin concomitant use
Serious toxicity with concomitant use of methotrexate and NSAIDs
Convulsions with quinolones and NSAIDs concomitant therapy
Increased frequency of unwanted effects with other NSAIDs and steroids
Lowered plasma levels when co-administered with aspirin

Contraindications

Hypersensitivity to any ingredient
Peptic ulcer
Hypersensitivity to Diclofenac
Contra-indicated in asthmatic patients affected by certain drugs
Not to be used under occlusive airtight dressings

Side Effects

Mild, rare, and transient adverse effects
Epigastric pain
Eructation
Nausea
Diarrhea
Dizziness
Headache
Peripheral edema
Skin reactions
Local irritation
Reddening of the skin
Skin rash

Pregnancy & Lactation

Employed only for compelling reasons during pregnancy
Lowest effective dose to be used during pregnancy
Not recommended during the first trimester of pregnancy
Very insignificant quantity detected in breast milk

Precautions & Warnings

Close observation in patients with peptic ulceration or gastrointestinal bleeding
Not to come in contact with eyes or mucus membranes
Proper hand washing after application
Not to be taken by mouth

Therapeutic Class

Drugs for Osteoarthritis
Drugs used for Rheumatoid Arthritis
Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Cool and dry place
Protected from light
Store below 30°C
Keep out of the reach of children

Related Brands