Benda DS 400 mg (Chewable Tablet)

Unit Price: ৳ 3.50 (50's pack: ৳ 175.00)

Medicine Details

Category Details
Generic Albendazole
Company Bristol pharmaceuticals ltd

Indications

  • Hookworm (Ancylostoma, Necator)
  • Roundworm (Ascaris)
  • Threadworm (Enterobius)
  • Whipworm (Trichuris)
  • Strongyloides
  • Tapeworm
  • Opisthorchi
  • Hydatid

Description

Benda DS is a benzimidazole anthelmintic, active against most nematodes and some cestodes. It is used in the treatment of intestinal nematode infections and in higher doses in the treatment of hydatid disease. Benda DS exhibits vermicidal, ovicidal, and larvicidal activity. The principal mode of action of Benda DS is its inhibitory effect on tubulin polymerization, which results in the loss of cytoplasmic microtubules.

Pharmacology

  • Broad spectrum anthelmintic
  • Vermicidal, ovicidal, and larvicidal activities
  • Blocking glucose uptake in susceptible helminths
  • Extensive first-pass metabolism
  • Anthelmintic activity of the metabolite albendazole sulphoxide

Dosage & Administration

  • Adults & children over 2 years:
    • 400 mg as a single dose for specific infections
    • 400 mg daily for strongyloidiasis or taeniasis for 3 days
  • Children of 1-2 years: Single dose of 200 mg
  • Hydatid disease (Echinococcosis):
    • 400 mg twice daily for patients over 60 kg
    • 15 mg/kg body weight daily in two divided doses for patients less than 60 kg
    • Cycles of treatment for cystic and alveolar echinococcosis
    • Giardiasis treatment for five days

Interaction

No reported pharmacodynamic or pharmacokinetic interactions

Contraindications

  • Neonates: Not normally used
  • Children: Possible dose reduction for children under 10 kg
  • Pregnant woman: Should not be given during pregnancy
  • Concurrent disease: No evidence for dose alteration in renal, hepatic, or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Reversible alopecia
  • Rash
  • Fever
  • Blood disorders
  • Allergic shock if cyst leakage
  • Convulsion and meningism in cerebral disease

Pregnancy & Lactation

Avoid use unless benefits outweigh risks

Precautions & Warnings

  • Blood counts and liver function tests before treatment and during each cycle
  • Breastfeeding considerations
  • Constant medical supervision for Echinococcosis treatment

Therapeutic Class

Anthelmintic

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children.

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