Voriderm 200 mg/5 ml (Powder for Suspension)
40 ml bottle: ৳ 1,000.00
Medicine Details
Category | Details |
---|---|
Generic | Voriconazole |
Company | Incepta pharmaceuticals ltd |
Also available as |
Indications
- Treatment of invasive aspergillosis
- Treatment of candidemia and disseminated candidiasis
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by specific fungal species
- Treatment for patients intolerant of or refractory to other therapy
Pharmacology
- Voriconazole is a triazole antifungal medication
- Inhibits ergosterol synthesis
- Binds and inhibits CYP450-dependent 14-alpha sterol demethylase
- Depletes ergosterol in fungal cell membrane
Dosage & Administration
- Oral administration instructions
- Loading dose regimen for different body weights
- Maintenance dose regimen for different body weights
- Injection administration instructions for specific infections
Interaction
- Interactions with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
- Increased concentrations of drugs that are CYP3A4, CYP2C9, and CYP2C19 substrates
- Co-administration effects with specific drugs like Phenytoin and Efavirenz
Contraindications
- Known hypersensitivity to Voriconazole or its components
- Co-administration risks with specific drugs
- Risk of loss of efficacy with certain co-administered drugs
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- Use during pregnancy justified only if potential benefit outweighs potential risk
Precautions & Warnings
- Careful assessment for long-term exposure greater than 180 days
- Association with squamous cell carcinoma of the skin in long-term treatment
Use in Special Populations
- Efficacy not established in children under 12 years of age
Overdose Effects
- No data available about overdose effects
Therapeutic Class
- Belongs to the class of Other Antifungal preparations
Reconstitution
- Instructions for reconstituting suspension
- Shaking the bottle before adding water
- Specific quantity of water to be added
- Storage conditions for reconstituted suspension
Storage Conditions
- Keep out of reach of children
- Store in a dry place below 25°C and protected from light
- Specific storage temperature for Voriderm powder for suspension