Seronex 25 mg (Tablet)
Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sertraline hydrochloride |
| Company | Renata limited |
| Also available as |
Indications
- Major depressive disorder (MDD)
- Obsessive-compulsive disorder (OCD)
- Panic disorder (PD)
- Post-traumatic stress disorder (PTSD)
- Social anxiety disorder (SAD)
- Premenstrual dysphoric disorder (PMDD)
Pharmacology
- Potent and selective inhibitory action on CNS neuronal reuptake of 5-HT
- Increased 5-HT concentrations at the synaptic clefts
- Facilitation of sustained activity at the postsynaptic receptor sites
- Reduction of Serotonin turnover in the brain
- Prolonged elimination half-life
- Once daily administration
Dosage & Administration
- Starting Dose: 50 mg for adults with Major depressive disorder and Obsessive-compulsive disorder
- Therapeutic Range: 50-200 mg for treatment of various disorders
- Starting Dose: 25 mg for adults with Panic disorder, Post-traumatic stress disorder, and Social anxiety disorder
- Starting Dose: 25 mg for pediatric patients with Obsessive-compulsive disorder
- Interval between dose changes: one week
- Starting dosage for PMDD is 50 mg/day
- Continuous or intermittent administration for PMDD
Interaction
- Potential effects of co-administration of drugs that are highly bound to plasma proteins
- Interactions with drugs such as Cimetidine, Diazepam, Hypoglycemic drugs, Atenolol
Contraindications
- Known hypersensitivity to Sertraline or any of the excipients
- Moderate to severe hepatic impairment
Side Effects
- Upset stomach
- Diarrhoea
- Constipation
- Vomiting
- Dry mouth
- Loss of appetite
- Weight changes
- Drowsiness
- Dizziness
- Headache
- Pain
- Burning or tingling in the hands or feet
- Excitement
- Sore throat
Pregnancy & Lactation
- Safety during human pregnancy not established
- Excretion in breast milk
- Discontinuation of breast-feeding should be considered if treatment is necessary
Precautions & Warnings
- Liver problems
- Kidney diseases
- Seizures
- Heart problems
- Allergies
- Dizziness or drowsiness
- Caution in activities requiring alertness
- Caution in the elderly
- Avoid use after taking monoamine oxidase inhibitor in the last five weeks
- Risk of suicidal thinking and change of behavior
Therapeutic Class
- SSRIs & related anti-depressant drugs
Storage Conditions
- Do not store above 30°C
- Keep out of the reach of children