Cosat (200 mg+40 mg)/5 ml (Oral Suspension)

60 ml bottle: ৳ 22.00

Medicine Details

Indications

  • Respiratory tract infections
  • Genito-urinary tract infections
  • Gastro-intestinal tract infections
  • Osteomyelitis
  • Brucellosis
  • Skin infections
  • Septicaemia
  • Bacillary dysentery
  • Cholera
  • Nocardiosis
  • Mycetoma

Pharmacology

  • Broad spectrum bactericidal activity
  • Gram-positive bacteria
  • Gram-negative bacteria
  • Protozoa
  • Biosynthesis of folinic acid

Dosage & Administration

  • Double strength tablet for age over 12 years
  • Mild to moderate infections
  • Severe infections
  • Long term therapy
  • Gonorrhoea
  • Tablet for age over 12 years
  • Suspension for age under 12 years

Contraindications

  • Hypersensitivity to trimethoprim or sulphonamides
  • Megaloblastic anaemia due to folate deficiency
  • Liver parenchymal damage
  • Blood dyscrasia
  • Severe renal insufficiency
  • Glucose 6-phosphate dehydrogenase deficiency

Side Effects

  • Crystalluria
  • Allergic reactions
  • Haemolysis
  • Thrombocytopenia
  • Neutropenia
  • Agranulocytosis
  • Malaise
  • Headache
  • Nausea
  • Vomiting

Pregnancy & Lactation

  • Excretion in breast milk
  • Kernicterus

Precautions & Warnings

  • Macrocytic anaemia risk
  • Folic acid conversion interference
  • Reversible with Folinic acid
  • Diabetic patients caution

Therapeutic Class

  • Anti-diarrhoeal Antimicrobial drugs
  • Sulphonamides
  • Trimethoprim

Storage Conditions

  • Below 30°C temperature
  • Away from light & moisture
  • Keep out of reach of children

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