Parlox 200 mg (Tablet)
Unit Price: ৳ 15.00 (1 x 10: ৳ 150.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sparfloxacin |
| Company | Eskayef pharmaceuticals ltd |
Product Title
- Parlox Antibacterial Tablets
Product Category
- Medicine
- Pharmaceuticals
Indications
- Community-acquired pneumonia treatment
- Chronic bronchitis treatment
- Chronic Obstructive Pulmonary Disease (COPD) treatment
- Sinusitis treatment
- Urinary tract infections treatment
- Bacterial prostatitis treatment
- Bacterial diarrhea treatment
- Osteomyelitis treatment
- Tuberculosis treatment
- Leprosy treatment
Microorganisms Targeted
- Chlamydia pneumoniae
- Haemophilus influenzae
- Haemophilus parainfluenzae
- Moraxella catarrhalis
- Mycoplasma pneumoniae
- Streptococcus pneumoniae
- Enterobacter cloacae
- Klebsiella pneumoniae
- Staphylococcus aureus
- Mycobacteria
- Chlamydia spp.
Mode of Action
- Inhibition of DNA gyrase and topoisomerase IV
- Killing bacteria in airways and lungs
- Effective against gram positive organisms
- Metabolism primarily by liver glucuronidation
Dosage & Administration
- 200mg tablets
- Loading dose on the first day
- Dosing frequency adjustment for renal impairment
Interaction
- Chelation with aluminium and magnesium cations in antacids and sucralfate
- No interaction with theophylline, caffeine, warfarin, cimetidine, or probenecid
Contraindications
- Hypersensitivity to ingredients
- Pregnancy and lactation
- Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency
- History of Achilles tendinitis following fluoroquinolones use
Side Effects
- Photosensitivity reaction
- Diarrhea
- Nausea
- Headache
- Dyspepsia
- Dizziness
- Insomnia
- Abdominal pain
- Pruritus
- Taste perversion
- QTc interval prolongation
- Vomiting
- Flatulence
- Vasodilatation
Pregnancy & Lactation
- Use justified if potential benefit outweighs risk to fetus
Precautions & Warnings
- Discontinuation at first signs of phototoxicity reaction
- Adequate hydration to prevent concentrated urine
- Caution in renal insufficiency
- Avoid concomitant QTc interval prolonging medications
- Avoid excessive sunlight exposure
Use in Special Populations
- No altered pharmacokinetics in the elderly with normal renal function
- No gender differences in pharmacokinetics
- Pharmacokinetics not studied in pediatric subjects
- Plasma concentration increase in renal impairment
- No alteration in mild or moderate hepatic impairment without cholestasis
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep out of reach of children
- Store away from heat and direct light
- Store below 30°C