Telmitan Plus 40 mg+12.5 mg (Tablet)
Unit Price: ৳ 12.50 (2 x 14: ৳ 350.00)
Strip Price: ৳ 175.00
Medicine Details
Category | Details |
---|---|
Generic | Telmisartan hydrochlorothiazide |
Company | Opsonin pharma ltd |
Also available as |
Indications
- Treatment of hypertension
- Lowering blood pressure
- Reducing the risk of cardiovascular events
- Can be used alone or with other antihypertensive agents
Pharmacology
- Telmisartan blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II
- Blocks the binding of angiotensin II to the AT1 receptor
- Does not inhibit ACE (kininase II)
- Hydrochlorothiazide affects renal tubular mechanisms of electrolyte reabsorption
Dosage & Administration
- Initial dose: Telmisartan monotherapy 80 mg or Hydrochlorothiazide 25 mg once daily
- Can be titrated up to Telmisartan and Hydrochlorothiazide 160 mg/25 mg after 2 to 4 weeks
- May be administered with other antihypertensive drugs
Interaction
- Caution with aliskiren, digoxin, lithium, other high blood pressure medicines
- Potential interference with certain laboratory tests
Contraindications
- Hypersensitivity to Telmisartan, Hydrochlorothiazide, or any other component
- Do not co-administer with Aliskiren in diabetic patients
Side Effects
- Dizziness
- Drowsiness
- Flushing
- Back pain
- Nausea
- Diarrhea
- Allergy
- Fever
- Leg pain
- Chest pain
- Insomnia
- Elevations of liver enzymes
- Leg cramps
Pregnancy & Lactation
- Pregnancy Category D
- Discontinue use during pregnancy as soon as possible
- Presence in human milk
- Thiazides appear in human milk
Precautions & Warnings
- Medical history consideration
- Effect on blood sugar
- Effect on potassium levels
- Potential dizziness
- Report prolonged diarrhea or vomiting
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- Caution in dose selection for elderly patients
- Close medical supervision for patients with biliary obstructive disorders or hepatic insufficiency
- Not recommended in severe renal impairment
Overdose Effects
- Manifestations of overdosage: hypertension, dizziness, tachycardia
- Not removed by hemodialysis
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep out of the reach of children
- Keep in a cool and dry place
- Protect from light
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