Fapravir 200 mg (Tablet)
Unit Price: ৳ 200.00 (1 x 10: ৳ 2,000.00)
Strip Price: ৳ 2,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Favipiravir |
| Company | Renata limited |
Indications
- Treatment of novel or re-emerging pandemic influenza virus infections
Description
- Approved for manufacture and sale in Japan as an influenza antiviral
- Selectively inhibits the RNA polymerase of the influenza virus
- Believed to be effective in treating COVID-19
- Production and distribution at the discretion of Japan’s Health, Labor and Welfare Ministry
Pharmacology
- Metabolized into favipiravir ribosyl triphosphate (favipiravir RTP) by an intracellular enzyme
- Selectively inhibits RNA polymerase of the influenza virus
- Effective against all types and sub-types of human influenza A, B, and C viruses in vitro
Dosage & Administration
- Usual adult dosage is 1600 mg twice daily on Day 1, followed by 600 mg twice daily from Day 2 to Day 5
- Total treatment duration should be 5 days
Interaction
- In animal studies, decreased RBC production
- Increases in liver function parameters such as AST, ALP, ALT, and total bilirubin
- Increased vacuolization in hepatocytes
Contraindications
- Contraindicated for pregnant women and women who may possibly be pregnant
Side Effects
- Most common side effects are diarrhea and increased blood uric acid levels
Pregnancy & Lactation
- May cause delayed development or death of embryos during the early stage of pregnancy
- Should not be given during pregnancy
Precautions & Warnings
- Should not be given to pregnant women
- Confirmation of non-pregnancy in women of childbearing potential before use
- Thorough contraception measures required from the start of the treatment to 7 days after the end of the treatment
- Caution for hepatic and renal impaired patients
Use in Special Populations
- Only approved as an experimental drug
- Studies needed about its efficacy, toxic reactions, and use in children
Overdose Effects
- In animal studies, decreased RBC production
Therapeutic Class
- Anti-viral drugs
Storage Conditions
- Keep below 30°C temperature
- Protected from light & moisture
- Keep out of the reach of children