Olzap 5 mg (Tablet)

Unit Price: ৳ 2.51 (5 x 14: ৳ 175.70)
Strip Price: ৳ 35.14

Medicine Details

Category Details
Generic Olanzapine
Company Opsonin pharma ltd
Also available as
Olzap 10 mg tablet

ProductTitle

  • Olzap

Categories

  • Medicine
  • Pharmaceutical

Description

  • Olzap is indicated for the acute and maintenance treatment of schizophrenia and related psychoses.
  • Olanzapine is an antipsychotic agent with affinities for serotonin 5HT2A/2C, dopamine D2, and other receptors.
  • The initial dose is 5-10 mg once daily for schizophrenia and bipolar disorder.
  • Olanzapine can be given without regard to meals.
  • Olzap may antagonize the effects of levodopa and dopamine agonists.
  • Olanzapine is contraindicated in patients with a known hypersensitivity to any ingredient and in patients with known risk for narrow-angle glaucoma.
  • Common undesirable effects include somnolence, weight gain, increased appetite, elevated glucose levels, and more.
  • Olanzapine should be used cautiously in patients with certain conditions and age groups.
  • Therapeutic Class: Atypical neuroleptic drugs.
  • Storage Conditions: Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Dimensions

    ColorOptions

      Functions

      • Treatment of Schizophrenia
      • Treatment of Related Psychoses
      • Treatment of Acute Manic or Mixed Episodes in Bipolar Disorder
      • Antipsychotic Agent
      • Maintenance Treatment

      Materials

        TechnicalSpecifications

        • Affinities for serotonin 5HT2A/2C, dopamine D2, and other receptors
        • Well absorbed after oral administration with peak plasma concentrations within 5 to 8 hours
        • Not mutagenic or clastogenic
        • Not carcinogenic

        DesignElements

          UsabilityFeatures

          • Can be given without regard to meals
          • Dosage may be adjusted based on individual clinical status
          • Maximum dosage is 20 mg daily
          • Can be administered with other drugs and alcohol with caution

          DosageOptions

          • Initial dose is 5-10 mg once daily for schizophrenia and bipolar disorder
          • Daily dosage may subsequently be adjusted within the range of 5-20 mg daily
          • Maximum dose is 20 mg daily

          StorageInstructions

          • Keep below 30°C temperature
          • Away from light & moisture
          • Keep out of the reach of children

          Interaction

          • May antagonize the effects of levodopa and dopamine agonists
          • Drugs that induce CYP1A2 or glucoronyl transferase enzymes may increase Olzap clearance
          • Inhibitors of CYP1A2 may potentially inhibit Olzap elimination
          • Carbamazepine may increase the clearance of Olzap
          • Concomitant administration of activated charcoal reduces the oral bioavailability of Olzap by 50-60%

          Contraindications

            SideEffects

            • Somnolence
            • Weight gain
            • Increased appetite
            • Elevated glucose levels
            • Elevated triglyceride levels
            • Dizziness
            • Akathisia
            • Parkinson's disease
            • Dyskinesia
            • Orthostatic hypotension
            • Mild and transient anticholinergic effects including constipation and dry mouth
            • Asthenia
            • Edema
            • Photosensitivity reaction

            PregnancyLactation

            • Should be used in pregnancy only if the potential benefits justify the potential risk to the fetus
            • No reports to show teratogenicity
            • Patients should not breastfeed if they are taking Olanzapine

            PrecautionsWarnings

            • Use cautiously in patients with a history of seizures or conditions associated with seizures
            • Use cautiously in patients with low leukocyte and/or neutrophil counts
            • Use cautiously in patients with certain hepatic, renal impairments, and age groups
            • Patients should be cautioned about operating hazardous machinery, including motor vehicles

            SpecialPopulations

            • Children: Olzap has not been studied in subjects under 18 years of age
            • Elderly patients (age 65 and over): Starting dose 5 mg/day
            • Patients with hepatic, renal impairment: Starting dose 5 mg/day

            Indication

            • Acute and maintenance treatment of schizophrenia and related psychoses

            Pharmacology

            • Affinity for various receptors
            • Proposed efficacy in schizophrenia through a combination of dopamine and serotonin type 2 (5HT2) antagonism
            • Well absorbed after oral administration, reaching peak plasma concentrations within 5 to 8 hours

            PediatricUses

              TherapeuticClass

              • Atypical neuroleptic drugs

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