D-Fill 20000 IU (Capsule)

Unit Price: ৳ 20.00 (1 x 10: ৳ 200.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Cholecalciferol vitamin d3
Company General pharmaceuticals ltd
Also available as
D fill 40000 iu capsule D fill 2000 iu capsule

Title and Categories

  • Vitamin D3 Supplement
  • Vitamin-D Preparations
  • Bone Health

Description

  • Essential for healthy bones and teeth
  • Prevents rickets, osteomalacia, osteoporosis
  • Vital role in immunity boost
  • Absorption of calcium and phosphate

Dosage and Administration

  • 40000 IU once weekly for adults with Vitamin D3 deficiency
  • 20000 IU every 4 weeks for prevention of deficiency in adults
  • 1000-2000 IU daily for film-coated tablets
  • Storage conditions: Keep below 30°C, protected from light & moisture

Pharmacology

  • Active form is Calcitriol
  • Binds to Vitamin D receptors (VDRs)
  • Absorbed in small intestine
  • Metabolized to 25-hydroxy Vitamin D3 and 1,25-dihydroxy Vitamin D3
  • Half-life of about 50 days

Interactions

  • Drugs causing deficiency: Magnesium-containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Cholistipol, Phenytoin, Phenobarbital, Orlistat, Mineral Oil
  • Corticosteroids increase the need for Vitamin D3

Contraindications

  • Hypercalcemia-associated diseases
  • Known hypersensitivity to Vitamin D3
  • Evidence of Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Lassitude
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Polyuria
  • Sweating
  • Headache
  • Thirst
  • Vertigo

Pregnancy & Lactation

  • Safe use up to 4000 IU during pregnancy
  • Recommended intake for pregnant women: 400 IU
  • Excreted in breast milk
  • Consider dose for breast-fed child

Precautions & Warnings

  • Monitor plasma-calcium concentration in high doses
  • Monitor in renal impairment, pregnancy, lactation
  • Consult healthcare practitioner with specific conditions

Use in Special Populations

  • Safety & efficacy not established in children under 12 years

Overdose Effects

  • Can lead to hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Keep below 30°C
  • Protected from light & moisture
  • Keep out of the reach of children

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