D-Fill 20000 IU (Capsule)
Unit Price: ৳ 20.00 (1 x 10: ৳ 200.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cholecalciferol vitamin d3 |
| Company | General pharmaceuticals ltd |
| Also available as |
Title and Categories
- Vitamin D3 Supplement
- Vitamin-D Preparations
- Bone Health
Description
- Essential for healthy bones and teeth
- Prevents rickets, osteomalacia, osteoporosis
- Vital role in immunity boost
- Absorption of calcium and phosphate
Dosage and Administration
- 40000 IU once weekly for adults with Vitamin D3 deficiency
- 20000 IU every 4 weeks for prevention of deficiency in adults
- 1000-2000 IU daily for film-coated tablets
- Storage conditions: Keep below 30°C, protected from light & moisture
Pharmacology
- Active form is Calcitriol
- Binds to Vitamin D receptors (VDRs)
- Absorbed in small intestine
- Metabolized to 25-hydroxy Vitamin D3 and 1,25-dihydroxy Vitamin D3
- Half-life of about 50 days
Interactions
- Drugs causing deficiency: Magnesium-containing Antacids, Digoxin, Thiazide Diuretics, Cholestyramine, Cholistipol, Phenytoin, Phenobarbital, Orlistat, Mineral Oil
- Corticosteroids increase the need for Vitamin D3
Contraindications
- Hypercalcemia-associated diseases
- Known hypersensitivity to Vitamin D3
- Evidence of Vitamin D3 toxicity
Side Effects
- Anorexia
- Lassitude
- Nausea & vomiting
- Diarrhea
- Constipation
- Weight loss
- Polyuria
- Sweating
- Headache
- Thirst
- Vertigo
Pregnancy & Lactation
- Safe use up to 4000 IU during pregnancy
- Recommended intake for pregnant women: 400 IU
- Excreted in breast milk
- Consider dose for breast-fed child
Precautions & Warnings
- Monitor plasma-calcium concentration in high doses
- Monitor in renal impairment, pregnancy, lactation
- Consult healthcare practitioner with specific conditions
Use in Special Populations
- Safety & efficacy not established in children under 12 years
Overdose Effects
- Can lead to hypervitaminosis D
Therapeutic Class
- Vitamin in bone formation
- Vitamin-D preparations
Storage Conditions
- Keep below 30°C
- Protected from light & moisture
- Keep out of the reach of children
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