Co-Diovan 80 mg+12.5 mg (Tablet)

Indications

• Treatment of hypertension

Pharmacology

• Oral medication
• Angiotensin receptor blockers (ARBs)
• Vasoconstrictor mechanism
• Blood pressure reduction
• Specific angiotensin II antagonist
• Renal tubular mechanisms
• Electrolyte reabsorption
• Diuretic action
• Aldosterone secretion reduction
• Plasma volume reduction
• Cardiovascular regulation
• AT1 receptor affinity

Dosage & Administration

• Combination therapy
• Maximum dose limits
• Elderly patient dosage
• Pediatric use safety

Interaction

• Interactions with diuretics
• Effect on serum potassium
• Interactions with lithium salts and other drugs
• Additive effects with antidiabetic and antihypertensive drugs
• Impairment of Hydrochlorothiazide absorption
• Warfarin and Digoxin interactions

Contraindications

• Hypersensitivity to components
• Anuria
• Hypersensitivity to sulfonamide-derived drugs

Side Effects

• Rare occurrence
• Common side effects like headache, dizziness, fatigue, abdominal pain, cough, nausea
• Potential side effects like hyperkalemia, impotency, reduced renal function, allergic reactions, constipation, muscle cramps, anxiety, insomnia, vertigo, hypotension

Pregnancy & Lactation

• Avoidance in pregnancy
• Fetal injury and death risks
• Excretion in human milk

Precautions & Warnings

• Hepatic impairment precautions
• Renal impairment precautions
• Caution in heart failure and myocardial infarction

Use in Special Populations

• Renal impairment regimens
• Hepatic impairment precautions

Overdose Effects

• Potential manifestations
• Management of Valsartan and Hydrochlorothiazide overdosage
• Signs and symptoms of electrolyte depletion
• Accentuated cardiac arrhythmias potential
• Hemodialysis removal

Therapeutic Class

• Combined antihypertensive preparations

Storage Conditions

• Temperature range for storage

Related Brands

• Cardival Plus 80 mg+12.5 mg (Tablet) - drug-international-ltd
• Cardival Plus 160 mg+12.5 mg (Tablet) - drug-international-ltd