Valsartil Plus 80 mg+12.5 mg (Tablet)

Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00

Medicine Details

Category Details
Generic Valsartan hydrochlorothiazide
Company Incepta pharmaceuticals ltd
Also available as
Valsartil plus 160 mg tablet

Indications

  • Treatment of hypertension

Pharmacology

  • Valsartan as an angiotensin receptor blocker (ARB)
  • Hydrochlorothiazide as a thiazide diuretic
  • Actions of Valsartan on AT1 subtype
  • Effects of Thiazides on renal tubular mechanisms

Dosage & Administration

  • Switch from monotherapy to combination for uncontrolled blood pressure
  • Dosage limit for Valsartan and Hydrochlorothiazide combination
  • No initial dosage adjustment required for elderly patients
  • Safety and effectiveness not established in pediatric patients

Interaction

  • Interaction of Valsartan with diuretics, agents increasing serum potassium, and lithium salts
  • Interaction of Hydrochlorothiazide with alcohol, barbiturates, narcotics, antidiabetic drugs, other antihypertensive drugs, cholestyramine, and colestipol resins

Contraindications

  • Hypersensitivity to any component of the product
  • Anuria
  • Hypersensitivity to sulfonamide-derived drugs

Side Effects

  • Headache
  • Dizziness
  • Fatigue
  • Abdominal pain
  • Cough
  • Diarrhea
  • Nausea
  • Hyperkalemia
  • Impotency
  • Reduced renal function
  • Allergic reactions
  • Dyspnea
  • Constipation
  • Back pain
  • Muscle cramps
  • Rash
  • Anxiety
  • Insomnia
  • Vertigo
  • Hypotension

Pregnancy & Lactation

  • Fetal injury and death in 2nd and 3rd trimester with Valsartan
  • Excretion of Hydrochlorothiazide in breast milk

Precautions & Warnings

  • Care needed in patients with impaired hepatic function
  • Dosage adjustment or discontinuation with pre-existing renal impairment
  • Caution in heart failure and post-myocardial infarction patients

Use in Special Populations

  • Usage in patients with renal impairment
  • Precautions in patients with hepatic impairment

Overdose Effects

  • Manifestations of Valsartan overdosage (hypotension and tachycardia)
  • Manifestations of Hydrochlorothiazide overdosage (electrolyte depletion)

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Store between 15-30°C

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