Deflaza 6 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute leukaemia
- Lymphatic leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
Anti-inflammatory action, inhibition of Phospholipase A2 enzyme, immunosuppressive action
Dosage & Administration
- Adults dosage range: 3-120 mg/day for acute disorders, 3-18 mg/day for most conditions, titration to lowest effective dose
- Children dosage range: 0.25-1.5 mg/kg/day, 0.25-1.0 mg/kg/day for juvenile chronic arthritis, 1.5 mg/kg/day for nephrotic syndrome
- Deflazacort withdrawal recommendations
Interaction
Metabolized in the liver, recommended dose adjustments for liver enzyme inducers and inhibitors
Contraindications
Hypersensitivity to ingredients, patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Myocardial rupture risk
- Thromboembolism risk
Pregnancy & Lactation
- Pregnancy: Potential risk of intrauterine growth retardation, benefits vs. risks should be considered
- Nursing Mother: Excreted in breast milk, potential systemic effects in infant, benefits likely outweigh theoretical risk at lower doses
Precautions & Warnings
- Special caution for cardiac disease or congestive heart failure
- Caution for gastritis, oesophagitis, ulcerative colitis, peptic ulcer
- Monitoring for diabetes mellitus, osteoporosis, myasthenia gravis, renal insufficiency
- Special caution for emotional instability, psychotic tendency, epilepsy
- Special caution for liver failure, hypothyroidism, cirrhosis, ocular herpes simplex
Use in Special Populations
- Hepatic Impairment: Dose monitoring and adjustment recommended
- Renal Impairment: No special precautions required
- Elderly: Common adverse effects may have more serious consequences
Therapeutic Class
Glucocorticoids
Storage Conditions
Store below 25°C, protected from light & moisture, keep out of reach of children