Klabid-DS 250 mg/5 ml (Powder for Suspension)
70 ml bottle: ৳ 700.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clarithromycin |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Acute bacterial exacerbation of chronic bronchitis in adults
- Acute maxillary sinusitis
- Community-acquired pneumonia
- Pharyngitis or tonsillitis
- Uncomplicated skin and skin structure infections
- Acute otitis media in pediatric patients
- Treatment and prophylaxis of disseminated mycobacterial infections
- Helicobacter pylori infection and duodenal ulcer disease in adults
Pharmacology
- Inhibits microsomal protein synthesis
- Binds to the donor site on the 50S subunit of the bacterial ribosome
- Active against most Gram-positive bacteria
- Active against Chlamydia, some Gram-negative bacteria and Mycoplasmas
- More acid-stable than Erythromycin
Dosage & Administration
- Specific dosing regimens for different indications
- Combination dosing regimens for H. pylori infection
- Dosage for pediatric patients
- Administration in renal and hepatic impairment
Interaction
- Contraindicated with specific medications
- Not recommended to use with certain antiarrhythmics drugs
Contraindications
- Hypersensitivity to clarithromycin or macrolide antibacterial drugs
- History of cholestatic jaundice or hepatic dysfunction associated with prior use of clarithromycin
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Abdominal pain
- Stomatitis
- Glossitis
- Headache
- Allergic reactions
- Taste perversion
- Transient central nervous system side effects
Pregnancy & Lactation
- Not recommended in pregnant patients
- Breast milk from mothers receiving Clarithromycin should not be given to infants
Precautions & Warnings
- Discontinue if severe acute hypersensitivity reactions occur
- Avoid in patients with known QT prolongation or receiving drugs known to prolong the QT interval
- Increased risk of all-cause mortality in patients with coronary artery disease
Use in Special Populations
- Safety and effectiveness in pediatric patients
- Special considerations for children and adolescents
Overdose Effects
- Gastro-intestinal symptoms
- Adverse reactions and treatment measures
Therapeutic Class
- Macrolides
Storage Conditions
- Store in a cool and dry place
- Protected from light & moisture
- Reconstituted suspension must be used within specific timeframes
- Keep out of reach of children