Saltide 100 mcg/puff (Inhaler)

Indications

• Treatment of bronchospasm in bronchial asthma
• Prevention of bronchospasm in bronchial asthma
• Treatment of reversible airway obstruction associated with bronchitis
• Treatment of reversible airway obstruction associated with emphysema
• Relief of exercise-induced bronchospasm
• Prophylactic use before exertion to prevent exercise-induced asthma

Pharmacology

• Selective β2-adrenoceptor agonist
• Acts on β2-adrenoceptors of bronchial smooth muscle
• Little or no action on β1-adrenoceptors of cardiac muscle
• Provides short-acting bronchodilatation (4-6 hours)
• Fast onset of action (within 5 minutes)
• Anti-inflammatory effect on mast cells
• Inhibition of release of bronchoconstrictor mediators

Dosage

• Administer by oral inhalation
• Shake well before each spray
• Adult maximum dose: 8 puffs in 24 hours
• Children maximum dose: Half the adult dose
• Prophylactic dose for exercise-induced bronchospasm
• Chronic therapy dose for adults and children

Administration

• Correct technique for effective inhalation
• Steps to use the inhaler as per National Asthma Guidelines for Medical Practitioners
• Instructions for cleaning the inhaler

Interaction

• Avoid concomitant use with non-selective beta-blocking drugs
• Potentially serious hypokalaemia from β2-agonist therapy
• Monitor serum potassium levels in certain situations

Contraindications

• History of hypersensitivity to salbutamol or any other components

Side Effects

• Tremors
• Anxiety
• Muscle cramps
• Headache
• Palpitation
• Increase in heart rate
• Cardiac arrhythmias
• Tachycardia
• Mouth and throat irritation

Pregnancy & Lactation

• Pregnancy Category C
• Use during pregnancy if potential benefit justifies potential risk to the fetus
• Caution when administered to a nursing woman

Precautions & Warnings

• Risk of paradoxical bronchospasm
• Clinically significant cardiovascular effects in some patients
• ECG changes such as flattening of the T wave
• Immediate hypersensitivity reactions
• Use with caution in patients with underlying cardiovascular disorders
• Use with caution in patients with convulsive disorders
• Use with caution in patients with hyperthyroidism
• Use with caution in patients with diabetes mellitus
• Use with caution in patients who are unusually responsive to sympathomimetic amines
• Aggravation of preexisting diabetes mellitus and ketoacidosis with large doses in intravenous administration

Use in Special Populations

• Safety and effectiveness in children 4 years of age and older have been established

Therapeutic Class

• Short-acting selective β2-adrenoceptor stimulants

Storage Conditions

• Pressurized canister
• Keep away from sunlight and heat
• Store below 30°C
• Do not freeze
• Keep away from eyes
• To be dispensed only on or by the prescription of a registered physician

Related Brands

• Salburen 100 mcg/puff (Inhaler) - renata-limited
• Proventa 100 mcg/puff (Inhaler) - opsonin-pharma-ltd