Seroquet ER 50 mg (Tablet (Extended Release))
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Acute and chronic psychoses treatment
- Schizophrenia treatment
- Bipolar disorder treatment
- Maintenance treatment of bipolar I disorder
- Manic episodes treatment
- Depressive episodes treatment
Pharmacology
- Atypical psychotropic agent
- Antagonist at multiple neurotransmitter receptors
- Serotonin 5HT1A and 5HT2 antagonist
- Dopamine D1 and D2 antagonist
- Histamine H1 antagonist
- Adrenergic α1 and α2 antagonist
Dosage & Administration
- Twice daily administration
- Day-wise dose titration
- Dosage adjustment based on clinical response
- Administer with or without food
- Usual effective dose range
- Daily dose for different indications
Interaction
- Caution with medicines causing electrolyte imbalance
- Caution with medicines increasing QT interval
- Co-administration effect on Seroquet clearance
Contraindications
- Hypersensitivity to Quetiapine
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Withdrawal symptoms
- Elevated serum triglyceride levels
- Elevated total cholesterol levels
- Weight gain
- Decreased haemoglobin
- Extrapyramidal symptoms
Pregnancy & Lactation
- Safety and efficacy during pregnancy not established
- Benefits vs. risks assessment during pregnancy
- Avoidance of breastfeeding while taking Quetiapine
Precautions & Warnings
- Risk of suicidal thoughts and clinical worsening in depression
- Caution in patients with cardiovascular disease
- Caution in patients with predisposition to hypotension
- Caution in patients with history of seizures
- Consideration of dose reduction for tardive dyskinesia symptoms
- Discontinuation and medical treatment for neuroleptic malignant syndrome
- Caution in patients with family history of QT prolongation
- Reported cases of severe neutropenia
- Observation of hyperglycemia and diabetes mellitus
Use in Special Populations
- Caution in elderly patients
- Lower therapeutic dose for the elderly
- Not indicated for use in children below 18 years of age
Overdose Effects
- Reported survival in acute overdoses
- No specific antidote
- Intensive care procedures recommended
- Management of refractory hypotension
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light