Tetrabez 25 mg (Tablet)

Unit Price: ৳ 35.00 (2 x 10: ৳ 700.00)
Strip Price: ৳ 350.00

Medicine Details

Indications

  • Treatment of chorea associated with Huntington's disease

Pharmacology

  • Vesicular monoamine transporter-2 (VMAT-2) inhibitor

Dosage & Administration

  • Can be taken with or without food
  • Individualization of dose with careful weekly titration required
  • Pediatric & geriatric use not established

Interaction

  • Strong CYP2D6 Inhibitors interaction
  • Reserpine interaction
  • No interaction with food

Contraindications

  • Actively suicidal or have untreated/undertreated depression
  • Hepatic impairment
  • Concurrent use of monoamine oxidase inhibitors (MAOIs) or reserpine
  • Concurrent use of deutetrabenazine or valbenazine

Side Effects

  • Common adverse reactions
  • Rare adverse reactions

Pregnancy & Lactation

  • No adequate data on developmental risk associated with use in pregnant women
  • No data on presence in human milk

Precautions & Warnings

  • Benefit and potential for adverse effects should be periodically re-evaluated
  • Maximum daily dose and single dose limitations
  • Neuroleptic Malignant Syndrome precautions
  • Impairment of ability to drive or operate machinery
  • Not recommended in combination with other drugs that prolong QTc

Overdose Effects

  • Drowsiness, sweating, and hypothermia may occur

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Store in a cool & dry place
  • Protect from light & moisture
  • Keep out of reach of children

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